Evidence map›Paper›PMID 35805091›Full record

ArticleCells2022

Some Preliminary Results to Eradicate Leukemic Cells in Extracorporeal Circulation by Actuating Doxorubicin-Loaded Nanochains of Fe

Xiawen Zheng, Xiaoli Mai, Siyuan Bao, Peng Wang, Yu Hong, Yuexia Han, Jianfei Sun, Fei Xiong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xiawen ZhengThe State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Sciences and Medical Engineering, Southeast University, Dingjiaqiao 87, Nanjing 210009, China.
Xiaoli MaiDrum Tower Hospital Affiliated to Medical School of Nanjing University, Zhongshan Road 321, Nanjing 210008, China.ORCID 0000-0002-2148-6877
Siyuan BaoThe State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Sciences and Medical Engineering, Southeast University, Dingjiaqiao 87, Nanjing 210009, China.
Peng WangDrum Tower Hospital Affiliated to Medical School of Nanjing University, Zhongshan Road 321, Nanjing 210008, China.
Yu HongThe State Key Laboratory of Natural Medicine, Department of Traditional Chinese Medicine, College of Chinese Materia Medica, China Pharmaceutical University, Nanjing 210009, China.
Yuexia HanTechnology and Engineering Center for Space Utilization, Chinese Academy of Sciences, Beijing 100094, China.
Jianfei SunThe State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Sciences and Medical Engineering, Southeast University, Dingjiaqiao 87, Nanjing 210009, China.ORCID 0000-0003-2204-0479
Fei XiongThe State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Sciences and Medical Engineering, Southeast University, Dingjiaqiao 87, Nanjing 210009, China.
State Key Laboratory of Digital Medical EngineeringNanjing Drum Tower Hospital · CNChina Pharmaceutical University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemia is a non-solid cancer which features the malignant proliferation of leukocytes. Excessive leukocytes of lesions in peripheral blood will infiltrate organs, resulting in intumescence and weakening treatment efficiency. In this study, we proposed a novel approach for targeted clearance of the leukocytes in the peripheral blood ex vivo, which employed magnetic nanochains to selectively destroy the leukocytes of the lesions. The nanochains were doxorubicin-loaded nanochains of Fe

Indexed as

LeukemiaNanoparticlesAnimalsDoxorubicinDrug CarriersExtracorporeal CirculationRatsDoxorubicinDrug Carriersdrug carrierextracorporeal circulationleukemiananochainsrotational magnetic field

Identifiers

PMID35805091
PMCPMC9265363
OpenAlexW4283385709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.