Evidence map›Paper›PMID 35805088›Full record

ArticleCells2022

A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle.

Rugivan Sabaratnam, Vibe Skov, Søren K Paulsen, Stine Juhl, Rikke Kruse, Thea Hansen, Cecilie Halkier, Jonas M Kristensen, Birgitte F Vind, Bjørn Richelsen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sarcopenic obesity: emerging mechanisms and therapeutic potential.Metabolism: clinical and experimental · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Rugivan SabaratnamSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.ORCID 0000-0002-4085-1083
Vibe SkovDepartment of Hematology, Zealand University Hospital, DK-4000 Roskilde, Denmark.ORCID 0000-0003-0097-7826
Søren K PaulsenDepartment of Pathology, Viborg Regional Hospital, DK-8800 Viborg, Denmark.
Stine JuhlSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.
Rikke KruseSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.
Thea HansenDepartment of Clinical Research, University of Southern Denmark, DK-5000 Odense C, Denmark.
Cecilie HalkierDepartment of Clinical Research, University of Southern Denmark, DK-5000 Odense C, Denmark.
Jonas M KristensenSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.
Birgitte F VindSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.
Bjørn RichelsenSteno Diabetes Center Aarhus, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.
Steen KnudsenAllarity Therapeutics Europe, DK-2970 Hørsholm, Denmark.
Jesper DahlgaardProgram for Mind and Body in Mental Health, Research Centre for Health and Welfare Technology, VIA University College, DK-8200 Aarhus, Denmark.
Henning Beck-NielsenSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.
Torben A KruseDepartment of Clinical Genetics, Odense University Hospital, DK-5000 Odense C, Denmark.
Kurt HøjlundSteno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense C, Denmark.ORCID 0000-0002-0891-4224
Steno Diabetes Centers · DKUniversity of Southern Denmark · DKAarhus University · DKMC2 Therapeutics (Denmark) · DKOdense University Hospital · DKRegionshospitalet Viborg · DKUniversity of Copenhagen · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin resistance in skeletal muscle in type 2 diabetes (T2D) is characterized by more pronounced metabolic and molecular defects than in obesity

Indexed as

Diabetes Mellitus, Type 2Insulin ResistanceAdiponectinAdipose TissueHumansMuscle, SkeletalObesityTranscriptional ActivationAdiponectinadipose tissue dysfunctionobesityskeletal muscletranscriptomicstype 2 diabetes

Identifiers

PMID35805088
PMCPMC9265693
OpenAlexW4283386828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.