Evidence map›Paper›PMID 35804977›Full record

ArticleCancers2022

Skin Surface Dose for Whole Breast Radiotherapy Using Personalized Breast Holder: Comparison with Various Radiotherapy Techniques and Clinical Experiences.

Chiu-Ping Chen, Chi-Yeh Lin, Chia-Chun Kuo, Tung-Ho Chen, Shao-Chen Lin, Kuo-Hsiung Tseng, Hao-Wen Cheng, Hsing-Lung Chao, Sang-Hue Yen, Ruo-Yu Lin and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Targeting the organelle for radiosensitization in cancer radiotherapy.Asian journal of pharmaceutical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Chiu-Ping ChenDepartment of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Chi-Yeh LinDepartment of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Chia-Chun KuoDepartment of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Tung-Ho ChenDepartment of Radiation Oncology, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan.
Shao-Chen LinGraduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Kuo-Hsiung TsengDepartment of Electrical Engineering, National Taipei University of Technology, Taipei 10608, Taiwan.
Hao-Wen ChengDepartment of Radiation Oncology, Shuang Ho Hospital, Taipei Medical University, Taipei 11031, Taiwan.
Hsing-Lung ChaoDepartment of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Sang-Hue YenDepartment of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Ruo-Yu LinDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Chen-Ju FengDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Long-Sheng LuDepartment of Radiation Oncology, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan.
Jeng-Fong ChiouDepartment of Radiation Oncology, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan.
Shih-Ming HsuDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Taipei Medical University · TWNational Yang Ming Chiao Tung University · TWWan Fang Hospital · TWNational Taipei University of Technology · TWTaipei Medical University Hospital · TWTri-Service General Hospital · TW

Funding

Ministry of Science and Technology MOST 106-2320-B-038-03Ministry of Science and Technology MOST-109-2314-B-038-122Ministry of Science and Technology MOST-109-2314-B-038-141Ministry of Science and Technology MOST-110-2314-B-038-138Ministry of Science and Technology MOST-110-2320-B-038-056National Health Research Institutes NHRI-EX109- 10713EITaipei Medical University TMU105-AE1-B13TMU Research Center of Cancer Translational Medicine DP2-109-21121-03-C-06-01TMU Research Center of Cancer Translational Medicine DP2-109-21121-03-C-06-02TMU Research Center of Cancer Translational Medicine DP2-109-21121-03-C-06-03TMU Research Center of Cancer Translational Medicine DP2-110-21121-03-C-06-01TMU Research Center of Cancer Translational Medicine DP2-110-21121-03-C-06-02TMU Research Center of Cancer Translational Medicine DP2-110-21121-03-C-06-03
6 · The paper itself

Abstract

purposeBreast immobilization with personalized breast holder (PERSBRA) is a promising approach for normal organ protection during whole breast radiotherapy. The aim of this study is to evaluate the skin surface dose for breast radiotherapy with PERSBRA using different radiotherapy techniques. MATERIALS AND

methodsWe designed PERSBRA with three different mesh sizes (large, fine and solid) and applied them on an anthropomorphic(Rando) phantom. Treatment planning was generated using hybrid, intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) techniques to deliver a prescribed dose of 5000 cGy in 25 fractions accordingly. Dose measurement with EBT3 film and TLD were taken on Rando phantom without PERSBRA, large mesh, fine mesh and solid PERSBRA for (a) tumor doses, (b) surface doses for medial field and lateral field irradiation undergoing hybrid, IMRT, VMAT techniques.

resultsThe tumor dose deviation was less than five percent between the measured doses of the EBT3 film and the TLD among the different techniques. The application of a PERSBRA was associated with a higher dose of the skin surface. A large mesh size of PERSBRA was associated with a lower surface dose. The findings were consistent among hybrid, IMRT, or VMAT techniques.

conclusionsBreast immobilization with PERSBRA can reduce heart toxicity but leads to a build-up of skin surface doses, which can be improved with a larger mesh design for common radiotherapy techniques.

Indexed as

breast cancerintensity-modulated radiotherapypersonalized breast holder (PERSBRA)radiotherapysurface dosevolumetric modulated arc therapy

Identifiers

PMID35804977
PMCPMC9264904
OpenAlexW4283738465

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.