Evidence map›Paper›PMID 35804914›Full record

ReviewCancers2022

Radon and Lung Cancer: Current Trends and Future Perspectives.

Mariona Riudavets, Marta Garcia de Herreros, Benjamin Besse, Laura Mezquita

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06196424 (Observational, Prospective, Multicentre Study to Investigate the Family History of Cancer in Patients With Non-small Cell Lung Cancer), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
28.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06196424 completednot on this mapstarted 2023, after this paper: background citation

Observational, Prospective, Multicentre Study to Investigate the Family History of Cancer in Patients With Non-small Cell Lung Cancer (FAHIC - Lung).

TypeobservationalSponsorFondazione Policlinico Universitario Campus Bio-MedicoRan2023 to 2025Enrolled336ConditionsNon Small Cell Lung CancerArmsstudy questionnaire to investigate family history
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 179 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mariona RiudavetsMedical Oncology Department, Gustave Roussy Cancer Campus, University Paris-Saclay, F-94800 Villejuif, France.
Marta Garcia de HerrerosMedical Oncology Department Hospital Clínic i Provincial de Barcelona, IDIBAPS, 08036 Barcelona, Spain.ORCID 0000-0001-8010-3584
Benjamin BesseMedical Oncology Department, Gustave Roussy Cancer Campus, University Paris-Saclay, F-94800 Villejuif, France.
Laura MezquitaMedical Oncology Department Hospital Clínic i Provincial de Barcelona, IDIBAPS, 08036 Barcelona, Spain.
Hospital Clínic de Barcelona · ESInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is a public health problem and the first cause of cancer death worldwide. Radon is a radioactive gas that tends to accumulate inside homes, and it is the second lung cancer risk factor after smoking, and the first one in non-smokers. In Europe, there are several radon-prone areas, and although the 2013/59 EURATOM directive is aimed to regulate indoor radon exposition, regulating measures can vary between countries. Radon emits alpha-ionizing radiation that has been linked to a wide variety of cytotoxic and genotoxic effects; however, the link between lung cancer and radon from the genomic point of view remains poorly described. Driver molecular alterations have been recently identified in non-small lung cancer (NSCLC), such as somatic mutations (

Indexed as

carcinogenesisdriver genomic alterationslung cancernon-smokersradon

Identifiers

PMID35804914
PMCPMC9264880
OpenAlexW4283644580

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.