Evidence map›Paper›PMID 35804905›Full record

ArticleCancers2022

Distribution of HPV Subtypes in Diverse Anogenital and Oral Samples from Women and Correlation of Infections with Neoplasia of the Cervix.

Karen Bräutigam, Stefanie Meier, Sabina Meneder, Louisa Proppe, Katharina Stroschein, Stephan Polack, Frank Köster, Achim Rody, Sascha Baum

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Karen BräutigamDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.ORCID 0000-0001-8521-9607
Stefanie MeierDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.
Sabina MenederDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.
Louisa ProppeDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.
Katharina StroscheinDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.
Stephan PolackDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.
Frank KösterDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.ORCID 0000-0001-8684-3698
Achim RodyDepartment of Gynecology and Obstetrics, Campus Lübeck, University Medical Center Schleswig-Holstein, 23538 Lübeck, Germany.
Sascha BaumGynäkologie des MVZ Westpfalz, 67655 Kaiserslautern, Germany.
University of Lübeck · DEWestpfalz Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancers and intraepithelial lesions of different anogenital areas as well as oral cancer are associated with human papilloma virus (HPV) infections.

methodsIn this study cervical, vaginal, vulvar, anal, and oral samples were taken from 509 patients visiting our dysplasia consultation clinic. HPV genotyping was performed using the EUROArray HPV test.

resultsPositivity of HR HPV was found in 60.4-64.3% of anogenital and 14.6% of oral samples. HPV 16 showed the highest incidence in all investigated areas. In cervical and vaginal samples HPV 31 was detected second most, while in vulvar, anal, and oral samples HPV 53 was the second most common subtype. HPV 18 was found lower in all areas, while HPV 51, HPV 52, and HPV 73 were detected higher than expected from published data. A good concordance between cervical, vaginal and vulvar samples was examined for most of the HPV. HR HPV infection was higher in cervical cancer (CC; 91.7%) and high-grade intraepithelial squamous lesions (HSIL; 93.9%) compared to low-grade SIL (LSIL; 69.6%) and normal samples (44.8%).

conclusionIn addition to the well described HPV subtypes, we found others with high incidences in the investigated areas which may be evident for HSIL and CC of those areas.

Indexed as

anogenital and oralcervical cancerhigh-risk HPVHPV subtype distributionintraepithelial lesion

Identifiers

PMID35804905
PMCPMC9264762
OpenAlexW4283574662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.