Evidence map›Paper›PMID 35804638›Full record

ReviewFoods (Basel, Switzerland)2022

Enhancing the Biological Activities of Food Protein-Derived Peptides Using Non-Thermal Technologies: A Review.

Gbemisola J Fadimu, Thao T Le, Harsharn Gill, Asgar Farahnaky, Oladipupo Odunayo Olatunde, Tuyen Truong

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Primary Metabolites in ThreeLife (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Review
  10. Advancements inFood chemistry: X · 2025
    Review
  11. Review
  12. Sustainable valorization ofFood chemistry: X · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Peas (Molecules (Basel, Switzerland) · 2025
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gbemisola J FadimuSchool of Science, RMIT University, Melbourne, VIC 3083, Australia.ORCID 0000-0003-4736-5106
Thao T LeDepartment of Food and Microbiology, Auckland University of Technology, Private Bag 92006, Auckland 1142, New Zealand.ORCID 0000-0002-1882-1961
Harsharn GillSchool of Science, RMIT University, Melbourne, VIC 3083, Australia.
Asgar FarahnakySchool of Science, RMIT University, Melbourne, VIC 3083, Australia.
Oladipupo Odunayo OlatundeDepartment of Food and Human Nutritional Sciences, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-1063-1995
Tuyen TruongSchool of Science, RMIT University, Melbourne, VIC 3083, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactive peptides (BPs) derived from animal and plant proteins are important food functional ingredients with many promising health-promoting properties. In the food industry, enzymatic hydrolysis is the most common technique employed for the liberation of BPs from proteins in which conventional heat treatment is used as pre-treatment to enhance hydrolytic action. In recent years, application of non-thermal food processing technologies such as ultrasound (US), high-pressure processing (HPP), and pulsed electric field (PEF) as pre-treatment methods has gained considerable research attention owing to the enhancement in yield and bioactivity of resulting peptides. This review provides an overview of bioactivities of peptides obtained from animal and plant proteins and an insight into the impact of US, HPP, and PEF as non-thermal treatment prior to enzymolysis on the generation of food-derived BPs and resulting bioactivities. US, HPP, and PEF were reported to improve antioxidant, angiotensin-converting enzyme (ACE)-inhibitory, antimicrobial, and antidiabetic properties of the food-derived BPs. The primary modes of action are due to conformational changes of food proteins caused by US, HPP, and PEF, improving the susceptibility of proteins to protease cleavage and subsequent proteolysis. However, the use of other non-thermal techniques such as cold plasma, radiofrequency electric field, dense phase carbon dioxide, and oscillating magnetic fields has not been examined in the generation of BPs from food proteins.

Indexed as

biological activityhigh-pressure processinghydrolysisnon-thermal technologypeptidesprotein modificationpulse electric fieldultrasonication

Identifiers

PMID35804638
PMCPMC9265340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.