Evidence map›Paper›PMID 35804222›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2022

A novel mitochondria-targetable NIR fluorescent probe for monitoring intracellular hypobromous acid levels.

Mingshuo Ma, Yuanyan Liu, Jie Chen, Shihua Yu, Zhigang Liu, Xiaodan Zeng

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mingshuo MaCenter of Characterization and Analysis, Jilin Institute of Chemical Technology, Jilin, People's Republic of China.
Yuanyan LiuJilin Petrochemical Company Quality Inspection Center, Jilin, People's Republic of China.
Jie ChenCenter of Characterization and Analysis, Jilin Institute of Chemical Technology, Jilin, People's Republic of China.
Shihua YuSchool of Chemical and Pharmaceutical Engineering, Jilin Institute of Chemical Technology, Jilin, People's Republic of China.
Zhigang LiuCenter of Characterization and Analysis, Jilin Institute of Chemical Technology, Jilin, People's Republic of China.
Xiaodan ZengCenter of Characterization and Analysis, Jilin Institute of Chemical Technology, Jilin, People's Republic of China. jiangzxd@163.com.ORCID http://orcid.org/0000-0003-2248-8388
Jilin University of Chemical Technology · CNHealth Commission of Jilin Province · CN

Funding

Education Department of Jilin Province 1564369511081Jilin Province Development and Reform Commission 2020C036-4Jilin Provincial Department of science and technology 20200901021SFJilin science and technology bureau 20190104190National Natural Science Foundation of China 22106051National Natural Science Foundation of China 51902125
6 · The paper itself

Abstract

The development of ultrasensitive in situ detection techniques for monitoring hypobromous acid (HBrO) levels in the biological systems is of great significance to reveal its complex pathological and physiological effects. A simple mitochondria-targetable hydrazine-based near-infrared (NIR) fluorescent probe (Mito-NIR) for detecting HBrO in the mitochondria of live cells is presented in this paper. Probe Mito-NIR displays the ultrafast (< 5 s) response for HBrO. It can detect HBrO with high sensitivity. Additionally, it shows high selectivity towards HBrO over other biologically important substances. Finally, it can monitor the changes of endogenous/exogenous HBrO levels in the mitochondria of live cells. A simple mitochondria-targetable NIR fluorescent probe with picomolar sensitivity for HBrO was developed to specifically track mitochondrial HBrO.

Indexed as

BromatesFluorescent DyesMitochondriaBromatesFluorescent Dyeshypobromous acidFluorescence bioimagingFluorescent probeHydrazineHypobromous acid (HBrO)Mitochondria-targetableNear-infrared fluorescence emission

Identifiers

PMID35804222
OpenAlexW4284967038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.