ArticleNPJ Parkinson's disease2022
Diurnal modulation of subthalamic beta oscillatory power in Parkinson's disease patients during deep brain stimulation.
Article in NPJ Parkinson's disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07244549 (Chronic Neurophyhsiological and Kinematic Biomarker Monitoring in Patients With Dystonia and Pallidal Deep Brain Stimulation), which is not on this map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Neurophyhsiological and Kinematic Biomarker Monitoring in Patients With Dystonia and Pallidal Deep Brain Stimulation
Who cites it
58 citing papers in PubMed.
- Adaptive deep brain stimulation for dynamic gait control in Parkinson's disease: a randomized feasibility trial.Nature medicine · 2026Trial
- Suppression of pathological oscillations with transcranial focused ultrasound in Parkinson's disease.Nature communications · 2026Trial
- Low-Frequency Deep Brain Stimulation in Non-Rapid Eye Movement Sleep Modifies Memory Retention in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Trial
- Chronic adaptive deep brain stimulation versus conventional stimulation in Parkinson's disease: a blinded randomized feasibility trial.Nature medicine · 2024Trial
- DBSsync: combining intracranial and multimodal data to investigate new biomarkers in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Multitarget brain implants enable generalized decoding of Parkinson's disease symptoms from chronic home recordings.Research square · 2026Article
- The biological clock in parkinson's disease: mechanisms and chronotherapy.NPJ Parkinson's disease · 2026Review
- Double Fault: Artifacts Produced by Physical Activity Can Impact the Efficacy of Chronic Local Field Potential Recordings and Adaptive Stimulation.Movement disorders clinical practice · 2026Article
- Real-Time ECG Artifact Removal for Adaptive Deep Brain Stimulation: A Comparative Study.Sensors (Basel, Switzerland) · 2026Article
- Common Electrophysiology Biomarkers Collected at Home Robustly Track Depression Recovery With Deep Brain Stimulation.medRxiv : the preprint server for health sciences · 2026Article
- Chronic adaptive deep brain stimulation in Parkinson's disease: ADAPT-START findings and programming principles.NPJ Parkinson's disease · 2026Article
- Low-frequency activity in the subthalamic nucleus informs about the acute neuropsychiatric state in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Excessive daytime sleepiness in parkinsonism is associated with cortical and basal ganglia beta oscillatory activity.Communications biology · 2026Article
- Temporal Dynamics of Beta Power Related to the Stun Effect in Parkinson's Disease Patients after Deep Brain Stimulation Surgery.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Slow wave electroencephalogram spectral properties during adaptation of a new light dark cycle in cynomolgus monkeys.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Proceedings of the 13th annual deep brain stimulation think tank: the evolving landscape.Frontiers in human neuroscience · 2026Review
- Subthalamic Theta-Alpha Local Field Potentials in OFF-Levodopa Dystonia in Parkinson's Disease.Movement disorders clinical practice · 2026Article
- Beta Power Response After Levodopa Intake in Parkinson's Disease Patients With Chronic Sensing-Enabled Deep Brain Stimulation.Annals of neurology · 2025Article
- A clinical grade neurostimulation implant for hierarchical control of physiological activity.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Beta-band activity in the subthalamic local field potential (LFP) is correlated with Parkinson's disease (PD) symptom severity and is the therapeutic target of deep brain stimulation (DBS). While beta fluctuations in PD patients are well characterized on shorter timescales, it is not known how beta activity evolves around the diurnal cycle, outside a clinical setting. Here, we obtained chronic recordings (34 ± 13 days) of subthalamic beta power in PD patients implanted with the Percept DBS device during high-frequency DBS and analysed their diurnal properties as well as sensitivity to artifacts. Time of day explained 41 ± 9% of the variance in beta power (p < 0.001 in all patients), with increased beta during the day and reduced beta at night. Certain movements affected LFP quality, which may have contributed to diurnal patterns in some patients. Future DBS algorithms may benefit from taking such diurnal and artifactual fluctuations in beta power into account.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.