Evidence map›Paper›PMID 35804025›Full record

ArticleScientific reports2022

First identification of bovine hepacivirus in wild boars.

Claudio de Martinis, Lorena Cardillo, Claudia Esposito, Maurizio Viscardi, Lorella Barca, Stefania Cavallo, Nicola D'Alessio, Vito Martella, Giovanna Fusco

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A novel genotype ofFrontiers in cellular and infection microbiology · 2025
    Article
  7. Article
  8. Two bovine hepacivirus genome sequences from U.S. cattle.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Claudio de MartinisUnit of Exotic and Vector-Borne Diseases, Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy.
Lorena CardilloUnit of Exotic and Vector-Borne Diseases, Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy. lorena.cardillo@izsmportici.it.
Claudia EspositoUnit of Exotic and Vector-Borne Diseases, Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy.
Maurizio ViscardiUnit of Exotic and Vector-Borne Diseases, Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy.
Lorella BarcaIstituto Zooprofilattico Sperimentale del Mezzogiorno, Calabria Section, Cosenza, Italy.
Stefania CavalloDepartment of Epidemiologic and Biostatistic Regional Observatory (OREB), Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Naples, Italy.
Nicola D'AlessioUnit of Exotic and Vector-Borne Diseases, Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy.
Vito MartellaDepartment of Veterinary Medicine, Aldo Moro" University, Bari, Italy.
Giovanna FuscoUnit of Exotic and Vector-Borne Diseases, Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy.
Istituto Zooprofilattico Sperimentale del Mezzogiorno · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is a major cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma in humans. Humans were long considered the only hosts of Hepacivirus. Recently HCV-like sequences have been found in several animal species. Hepaciviruses are considered species-specific but a wider host range and a zoonotic role has been hypothesized. We report the first detection of bovine hepacivirus (BovHepV) sequences in wild boars. A total of 310 wild boars hunted in Campania region were investigated with a pan-hepacivirus nested-PCR protocol for the NS3 gene. Hepacivirus RNA was detected in 5.8% of the animals. Sequence and phylogenetic analysis showed high homology with BovHepV subtype F, with nucleotide identity of 99%. The positive wild boars were georeferenced, revealing high density of livestock farms, with no clear distinction between animal husbandry and hunting areas. These findings might suggest the ability of BovHepV to cross the host-species barrier and infect wild boars.

Indexed as

HepacivirusHepatitis CAnimalsCattleHost SpecificityPhylogenySus scrofaSwine

Identifiers

PMID35804025
PMCPMC9270363
OpenAlexW4284974190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.