ArticleScientific reports2022
Performance and reproducibility of
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Hyperpolarized [2-NMR in biomedicine · 2026Article
- Exploring Limits of [1-Small science · 2026Article
- Minute-Scale Repeated Metabolic Probing of Living Cells Enabled by Rapid Parahydrogen-Based Hyperpolarization.Angewandte Chemie (International ed. in English) · 2026Article
- Phenylalanine Versus Tyrosine (Pos. 367/332 in MCT1/MCT4) in the Substrate Binding Site Defines Affinity and Preferred Directionality of Human Monocarboxylate Transporters 1-4.Acta physiologica (Oxford, England) · 2026Article
- Feasibility of co-polarizing ¹³C-pyruvate and ¹³C-tert-butanol for simultaneous metabolic and perfusion imaging.Npj imaging · 2026Article
- Across-cities transportableNature communications · 2026Article
- Field Cycling from 10 nT to 9.4 T: A Flexible Gear Rod Design for Nuclear Spin Relaxation and Hyperpolarization Studies.ACS measurement science au · 2026Article
- Upscaling the Hyperpolarization Sample Volume of an Automated Hydrogenative Parahydrogen-Induced Polarizer.ACS measurement science au · 2025Article
- Nuclear spin hyperpolarization of pyruvate enables longitudinal monitoring of treatment response in intestinal tumor organoids.Magnetic resonance in medicine · 2025Article
- Chemically induced deceleration of nuclear spin relaxation (CIDER) preserves hyperpolarization.Science advances · 2025Article
- Maximizing NMR Sensitivity: A Guide to Receiver Gain Adjustment.NMR in biomedicine · 2025Article
- Carbon-13 Hyperpolarization of α-Ketocarboxylates with Parahydrogen in Reversible Exchange.ChemMedChem · 2025Article
- Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025Review
- Overcoming the Challenges of Hyperpolarizing Substrates with Parahydrogen-Induced Polarization in an MRI System.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Yeast Solutions and Hyperpolarization Enable Real-Time Observation of Metabolized Substrates Even at Natural Abundance.Analytical chemistry · 2024Article
- Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer.Communications chemistry · 2024Article
- Nuclear spin polarization of lactic acid via exchange of parahydrogen-polarized protons.Communications chemistry · 2024Article
- Current methods for hyperpolarized [1-Magnetic resonance in medicine · 2024Review
- Parahydrogen-Polarized [1-Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions.Science advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The setup, operational procedures and performance of a cryogen-free device for producing hyperpolarized contrast agents using dissolution dynamic nuclear polarization (dDNP) in a preclinical imaging center is described. The polarization was optimized using the solid-state, DNP-enhanced NMR signal to calibrate the sample position, microwave and NMR frequency and power and flip angle. The polarization of a standard formulation to yield ~ 4 mL, 60 mM 1-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.