Evidence map›Paper›PMID 35803955›Full record

ArticleScientific reports2022

Inactivity and Ca

Tanya Zubov, Lara do Amaral-Silva, Joseph M Santin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tanya ZubovDepartment of Biology, The University of North Carolina at Greensboro, Greensboro, USA.
Lara do Amaral-SilvaDepartment of Biology, The University of North Carolina at Greensboro, Greensboro, USA.
Joseph M SantinDepartment of Biology, The University of North Carolina at Greensboro, Greensboro, USA. jmsantin@uncg.edu.
University of North Carolina at Greensboro · US

Funding

Homeostatic plasticity mechanisms regulate behavior in vivoR01NS114514 · NINDS · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI Joseph M Santin · 2021 to 2026
$1.5M
Acquiring resistance to anoxia in neural circuit functionR15NS112920 · NINDS · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI OSENA, AYALEW LIGABA · 2020 to 2020
$355k
NIH HHS 1R01NS114514NINDS NIH HHS R01 NS114514NINDS NIH HHS R15 NS112920
6 · The paper itself

Abstract

Neural networks tune synaptic and cellular properties to produce stable activity. One form of homeostatic regulation involves scaling the strength of synapses up or down in a global and multiplicative manner to oppose activity disturbances. In American bullfrogs, excitatory synapses scale up to regulate breathing motor function after inactivity in hibernation, connecting homeostatic compensation to motor behavior. In traditional models of homeostatic synaptic plasticity, inactivity is thought to increase synaptic strength via mechanisms that involve reduced Ca

Indexed as

HibernationAnimalsMotor NeuronsNeuronal PlasticityRana catesbeianaSynapsesTetrodotoxinTetrodotoxin

Identifiers

PMID35803955
PMCPMC9270477
OpenAlexW4284896951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.