ArticleAnais brasileiros de dermatologia
Intraoperative assessment of surgical margins using "en face" frozen sections in the management of cutaneous carcinomas.
Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 10 citations in OpenAlex.
- Routine Frozen Section Analysis May Be Omittable for Nodular Basal Cell Carcinoma Undergoing Local Flap Reconstruction.Cancers · 2026Article
- Intraoperative Margin Control in Eyelid Tumor Surgery: Current Standards, Imaging Advances, and Emerging Techniques.Current oncology (Toronto, Ont.) · 2026Review
- Frozen Section Mohs: A Hybrid Technique and One Plastic Surgeon's Experience With 1714 Consecutive Skin Cancer Removals.Annals of plastic surgery · 2025Article
- Hyperspectral imaging with machine learning for in vivo skin carcinoma margin assessment: a preliminary study.Physical and engineering sciences in medicine · 2024Article
- Recurrence rates of periocular basal cell carcinoma following intra-operative en-face frozen section margin controlled excision.Irish journal of medical science · 2024Article
- Insight on common forms of cutaneous head and neck carcinoma (Review).Molecular and clinical oncology · 2023Review
- On the recurrence rate of cutaneous tumors treated exclusively by micrographic surgery.Anais brasileiros de dermatologiaArticle
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5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBasal cell and squamous cell carcinomas (BCC and SCC) are the most common types of cancer worldwide. Intraoperative assessment of surgical margins by frozen section has been widely used to ensure disease-free margins. The intraoperative "en face" freezing technique evaluates all peripheral and deep margins.
objectiveTo report the results of the "en face" freezing technique in relation to tumor recurrence and agreement with paraffin-embedded tissue examination.
methodsRetrospective analysis of patients undergoing surgical excision of BCC and SCC at the A. C. Camargo Cancer Center, Brazil.
resultsThis study included 542 skin carcinomas, which were excised from 397 patients. A total of 201 male patients (50.6%), and 196 female patients (49.4%) were assessed, whose mean age was 64 years. The tumors were mostly located on the head and neck region (87.8%). BCC corresponded to 79.7% of the cases. The mean follow-up was 38 months. Tumor relapse occurred in 0.86% of the primary tumors and 3.7% of recurrent tumors. The result of the intraoperative "en face" frozen section evaluation was in agreement with the final result of the anatomopathological examination (paraffin test) in 98% of the lesions. STUDY LIMITATIONS: Not having a minimum follow-up time of 5 years for all patients.
conclusionThe "en face" freezing technique shows low tumor relapse, being reliable and safe to guarantee negative surgical margins of the tumor.
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