Evidence map›Paper›PMID 35803731›Full record

ArticleJournal of neurointerventional surgery2023

Aneurysm treatment with the Woven EndoBridge (WEB) device in the combined population of two prospective, multicenter series: 5-year follow-up.

Laurent Pierot, Istvan Szikora, Xavier Barreau, Markus Holtmannspoetter, Laurent Spelle, Joachim Klisch, Denis Herbreteau, Vincent Costalat, Jens Fiehler, Anne-Christine Januel and 7 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01778322 (WEB Clinical Assessment of IntraSaccular Aneurysm Therapy), which is not on this map. Cited by 51 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01778322 completednot on this map

WEB Clinical Assessment of IntraSaccular Aneurysm Therapy

TypeobservationalSponsorMicrovention-Terumo, Inc.Ran2011 to 2019Enrolled51ConditionsIntracranial AneurysmArmsIntracranial aneurysm embolization
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Long-term outcomes of the Woven EndoBridge device for treatment of intracranial aneurysms: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Aneurysmal recurrence and retreatment modalities after Woven EndoBridge (WEB) device implantation: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
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  6. Article
  7. The Aristotle 18 and 24 microwires in neuroIntervention: Early experience at a single centre.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  8. Woven EndoBridge versus stent-assisted coil embolization for the treatment of ruptured wide-necked aneurysms: A multicentric experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  9. A case report and literature review of multiple complications in the treatment of an aneurysm with the woven endobridge device.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
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  12. Persistent flow inside the Woven EndoBridge at angiographic follow-up: A multicenter study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  20. The application of silent MRA in follow-up after intracranial aneurysm endovascular treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Laurent PierotDepartment of Neuroradiology, CHU Reims, Reims, Champagne-Ardenne, France lpierot@gmail.com.ORCID http://orcid.org/0000-0002-2523-4909
Istvan SzikoraNeurointerventions, National Institute of Clinical Neurosciences, Budapest, Hungary.ORCID http://orcid.org/0000-0003-3730-3278
Xavier BarreauNeuroradiology Department, CHU Bordeaux GH Pellegrin, Bordeaux, Aquitaine, France.
Markus HoltmannspoetterInterventional and Diagnostic Neuroradiology, Nuremberg Hospital Campus South, Nurnberg, Germany.ORCID http://orcid.org/0000-0003-2536-5244
Laurent SpelleNEURI Interventional Neuroradiology, APHP, Paris, Île-de-France, France.ORCID http://orcid.org/0000-0002-6748-8528
Joachim KlischNeuroradiology, Helios Klinikum Erfurt, Erfurt, Thüringen, Germany.
Denis HerbreteauNRI, CHU Tours, Tours, France.
Vincent CostalatNeuroradiology, CHU Montpellier, Montpellier, Languedoc-Roussillon, France.
Jens FiehlerDepartment of Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-8533-7478
Anne-Christine JanuelNeuroradiology, CHU Toulouse, Toulouse, Occitanie, France.
Thomas LiebigDepartment of Neuroradiology, University Hospital Munich, Munchen, Bayern, Germany.
Luc StockxNeuroradiology, Ziekenhuis Oost-Limburg, Genk, Limburg, Belgium.
Werner WeberRadiology and Neuroradiology, Ruhr-Universität Bochum, Bochum, Nordrhein-Westfalen, Germany.
Joachim BerkefeldInstitute of Neuroradiology, Goethe-Universitat Frankfurt am Main, Frankfurt am Main, Hessen, Germany.
Jacques MoretNEURI Interventional Neuroradiology, APHP, Paris, Île-de-France, France.
Andy MolyneuxNeurovascular and Neuroradiology Research Unit, Oxford University, Oxford, UK.
James ByrneDepartment of Neuroradiology, Oxford University, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvaluating a new endovascular treatment for intracranial aneurysms must not only demonstrate short-term safety and efficacy, but also evaluate longer-term outcomes (eg, delayed complications, anatomical results, retreatment). The current analysis reports the 5-year clinical and anatomical results of Woven EndoBridge (WEB) treatment in two European combined trial populations (WEBCAST (WEB Clinical Assessment of Intrasaccular Aneurysm Therapy) and WEBCAST-2).

methodsAll adverse events occurring between the procedure and 5-year follow-up were independently evaluated by an expert. Aneurysm occlusion was evaluated by an independent core laboratory using a three-grade scale: complete occlusion, neck remnant, and aneurysm remnant. In cases where data were not available at 5-year follow-up, the last observation carry forward (LOCF) method was used.

resultsThe safety and efficacy populations comprised 100 patients and 95 aneurysms, respectively. No adverse event related to the device occurred after the procedure during the 5-year follow-up period. Mortality at 5 years was 7.0% (7/100 patients) including mortality related to the WEB (0/100, 0.0%), the procedure (1/100, 1.0%), and another condition (6/100, 6.0%). At 5 years, complete aneurysm occlusion was observed in 49/95 (51.6%) aneurysms, neck remnant in 25/95 (26.3%), and aneurysm remnant in 21/95 (22.1%). Retreatment rate at 5 years was 11.6% (11/95 aneurysms).

conclusionsThis analysis conducted in a population of patients with wide-neck bifurcation aneurysms confirms WEB's safety profile. Additional evidence demonstrates good stability of aneurysm occlusion with adequate occlusion (complete occlusion or neck remnant) at 5 years in 77.9% of aneurysms with a low retreatment rate (11.6%). CLINICAL

trial registrationWEBCAST and WEBCAST-2: Unique identifier: NCT01778322.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmFollow-Up StudiesHumansProspective StudiesRetrospective StudiesTreatment OutcomeAneurysm

Identifiers

PMID35803731
PMCPMC10314010

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.