ArticleJournal of neurointerventional surgery2023
Preoperative tumor embolization prolongs time to recurrence of meningiomas: a retrospective propensity-matched analysis.
Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Standalone Meningioma Embolization: A Systematic Review.Neurosurgery · 2026Pooled it
- Comparative benefits of particle embolization versus liquid agents in preoperative management of meningiomas: A Systematic Review and Meta-analysis.The neuroradiology journal · 2026Pooled it
- Preoperative Embolization of Meningiomas Facilitates Reduced Surgical Complications and Improved Clinical Outcomes : A Meta-analysis of Matched Cohort Studies.Clinical neuroradiology · 2023Pooled it
- Outcomes of Preoperative Transophthalmic Artery Embolization of Meningiomas: A Systematic Review with a Focus on Embolization Agent.AJNR. American journal of neuroradiology · 2023Pooled it
- A comprehensive review on the current applications and future perspectives of radioembolization in endovascular neurosurgery.Journal of neurointerventional surgery · 2026Review
- Pre-operative embolization of skull base meningiomas.Neuro-oncology advances · 2026Review
- Preoperative embolization in intracranial meningioma surgery: An updated systematic review and meta-analysis.Surgical neurology international · 2026Review
- Preoperative embolization improves local control and modulates gene expression in atypical WHO grade 2 meningioma.Neuro-oncology · 2025Article
- Embolization of Meningiomas with Ultralow Concentration N-Butyl 2-Cyanoacrylate.Asian journal of neurosurgery · 2025Article
- Article
- Real-world Experience of Embolization for Intracranial Tumors in Japan: Analysis of 2,756 Cases from Japanese Registry of NeuroEndovascular Therapy 4.Neurologia medico-chirurgica · 2025Observational
- Intraoperative neurovascular considerations for efficient intraventricular meningioma surgery: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Embolization of Posterior Fossa Meningiomas Supplied with Meningohypophyseal Trunk by UsingAJNR. American journal of neuroradiology · 2025Article
- Article
- Article
- Tumor Embolization via the Meningohypophyseal and Inferolateral Trunk in Patients with Skull Base Tumors Using the Distal Balloon Protection Technique.AJNR. American journal of neuroradiology · 2024Article
- Article
- Differences and Advantages of Particles versus Liquid Material for Preoperative Intracranial Tumor Embolization: A Retrospective Multicenter Study.Journal of neuroendovascular therapy · 2024Article
- Surgical complications and recurrence factors for asymptomatic meningiomas: a single-center retrospective study.Acta neurochirurgica · 2023Article
- Intravital tumor decellularization as a new approach to cancer treatment.American journal of cancer research · 2023Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMeningiomas are often embolized preoperatively to reduce intraoperative blood loss and facilitate tumor resection. However, the procedure is controversial and its effects have not yet been reported. We evaluated preoperative embolization for meningiomas and its effect on postoperative outcome and recurrence.
methodsWe retrospectively reviewed the medical records of 186 patients with WHO grade I meningiomas who underwent surgical treatment at our hospital between January 2010 and December 2020. We used propensity score matching to generate embolization and no-embolization groups (42 patients each) to examine embolization effects.
resultsPreoperative embolization was performed in 71 patients (38.2%). In the propensity-matched analysis, the embolization group showed favorable recurrence-free survival (RFS) (mean 49.4 vs 24.1 months; Wilcoxon p=0.049). The embolization group had significantly less intraoperative blood loss (178±203 mL vs 221±165 mL; p=0.009) and shorter operation time (5.6±2.0 hours vs 6.8±2.8 hours; p=0.036). There were no significant differences in Simpson grade IV resection (33.3% vs 28.6%; p=0.637) or overall perioperative complications (21.4% vs 11.9%; p=0.241). Tumor embolization prolonged RFS in a subanalysis of cases who experienced recurrence (n=39) among the overall cases before variable control (mean RFS 33.2 vs 16.0 months; log-rank p=0.003).
conclusionsAfter controlling for variables, preoperative embolization for meningioma did not improve the Simpson grade or patient outcomes. However, it might have effects outside of surgical outcomes by prolonging RFS without increasing complications.
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