Evidence map›Paper›PMID 35803332›Full record

ArticleExperimental eye research2022

Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease.

Vanessa S Goodwill, Ian Dryden, Jihee Choi, Chiara De Lillo, Katrin Soldau, Jorge Llibre-Guerra, Henry Sanchez, Christina J Sigurdson, Jonathan H Lin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. TDP43 pathology in chronic traumatic encephalopathy retinas.Acta neuropathologica communications · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Vanessa S GoodwillDepartment of Pathology, University of California, San Diego, CA, 92093, USA. Electronic address: VGoodwill@health.ucsd.edu.
Ian DrydenDepartments of Pathology and Ophthalmology, Stanford University, CA, 94305, USA; VA Palo Alto Healthcare System, Palo Alto, CA, 94304, USA.
Jihee ChoiDepartments of Pathology and Ophthalmology, Stanford University, CA, 94305, USA; VA Palo Alto Healthcare System, Palo Alto, CA, 94304, USA.
Chiara De LilloDepartments of Pathology and Ophthalmology, Stanford University, CA, 94305, USA.
Katrin SoldauDepartment of Pathology, University of California, San Diego, CA, 92093, USA.
Jorge Llibre-GuerraDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, 63108, USA; Global Brain Health Institute, University of California, San Francisco, CA, 94143, USA.
Henry SanchezDepartment of Neurology, University of California, San Francisco, CA, 94143, USA.
Christina J SigurdsonDepartment of Pathology, University of California, San Diego, CA, 92093, USA.
Jonathan H LinDepartments of Pathology and Ophthalmology, Stanford University, CA, 94305, USA; VA Palo Alto Healthcare System, Palo Alto, CA, 94304, USA. Electronic address: Jonathan.H.Lin@stanford.edu.
University of California San Diego · USVA Palo Alto Health Care System · USUniversity of California, San Francisco · USStanford University · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Yang Hu · 2017 to 2026
$8.0M
Mechanisms of Prion Aggregation and Species BarriersR01NS069566 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESKO, JEFFREY D, RAVITS, JOHN · 2011 to 2025
$5.7M
Mechanisms of Prion SpreadR01NS076896 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2012 to 2021
$3.4M
Protein Homeostasis and Proteotoxicity MechanismsR01NS088485 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIN, JONATHAN · 2015 to 2024
$3.0M
Mechanisms of Prion Spread and Neuronal ToxicityR37NS076896 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Christina Sigurdson · 2023 to 2026
$2.6M
Molecular basis of prion protein-induced neurodegenerationRF1NS121992 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2021 to 2023
$1.7M
Molecular basis of prion protein-induced neurodegenerationR01NS121992 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2024 to 2025
$963k
Endoplasmic Reticulum Stress in NeurodegenerationI01RX002340 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI JONATHAN LIN · 2017 to 2026
–
Cellular and Molecular Mechanisms of Age-Related Retinal DegenerationI01BX002284 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI LIN, JONATHAN · 2014 to 2023
–
BLRD VA I01 BX002284NEI NIH HHS P30 EY026877NINDS NIH HHS R01 NS069566NINDS NIH HHS R01 NS076896NINDS NIH HHS R01 NS088485NINDS NIH HHS R01 NS121992NINDS NIH HHS R37 NS076896NINDS NIH HHS RF1 NS121992RRD VA I01 RX002340
6 · The paper itself

Abstract

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most commonly diagnosed human prion disease caused by the abnormal misfolding of the 'cellular' prion protein (PrP

Indexed as

Creutzfeldt-Jakob SyndromePrionsRetinal DiseasesBrainGliosisHumansRetinaPrionsBrainEyeImmunohistochemistryPrionRetinaSpongiform encephalopathysporadic Creutzfeldt-Jakob disease

Identifiers

PMID35803332
PMCPMC9946801
OpenAlexW4284990468

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.