ArticleNeuron2022
Thalamic bursting and the role of timing and synchrony in thalamocortical signaling in the awake mouse.
Article in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
- The cerebellum exploits a thalamic carrier frequency to refine motor behaviors.bioRxiv : the preprint server for biology · 2026Article
- Thalamocortical bursts encode reward contingencies and drive associative learning.Nature communications · 2026Article
- Article
- EphB1-NR2B receptor signaling in glutamatergic neurons of the ventroposteromedial thalamic nucleus regulates emergence from anesthesia.Science advances · 2025Article
- Impaired thalamic burst firing in fragile X syndrome.Cell reports · 2025Article
- Layer 6 Corticothalamic Neurons Induce High Gamma Oscillations Through Cortico-cortical and Cortico-thalamo-cortical Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Causal role for pulvinar burst firing in thalamo-cortical attention control.bioRxiv : the preprint server for biology · 2025Article
- Experience-Dependent Intrinsic Plasticity in Layer IV of Barrel Cortex at Whisking Onset.eNeuro · 2025Article
- A tactile discrimination task to study neuronal dynamics in freely-moving mice.Nature communications · 2025Article
- Thalamic burst and tonic firing selectively indicate patients' consciousness level and recovery.Innovation (Cambridge (Mass.)) · 2025Article
- A model of thalamo-cortical interaction for incremental binding in mental contour-tracing.PLoS computational biology · 2025Article
- Evolution Trend of Brain Science Research: An Integrated Bibliometric and Mapping Approach.Brain and behavior · 2025Review
- Immediately following the onset of active whisking, the input layer of barrel cortex exhibits a transient period of increased excitability that depends on prior experience.bioRxiv : the preprint server for biology · 2025Article
- Thalamic feedback shapes brain responses evoked by cortical stimulation in mice and humans.Nature communications · 2025Article
- Multiple Distinct Timescales of Rapid Sensory Adaption in the Thalamocortical Circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Synaptic facilitation and learning of multiplexed neural signals.Frontiers in network physiology · 2025Article
- MULTIPLE DISTINCT TIMESCALES OF RAPID SENSORY ADAPATION IN THE THALAMOCORTICAL CIRCUIT.bioRxiv : the preprint server for biology · 2024Article
- Article
- Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales.PLoS biology · 2024Article
- Dynamic corticothalamic modulation of the somatosensory thalamocortical circuit during wakefulness.Nature communications · 2024Article
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6 authors at 3 institutions in 1 country.
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Abstract
The thalamus controls transmission of sensory signals from periphery to cortex, ultimately shaping perception. Despite this significant role, dynamic thalamic gating and the consequences for downstream cortical sensory representations have not been well studied in the awake brain. We optogenetically modulated the ventro-posterior-medial thalamus in the vibrissa pathway of the awake mouse and measured spiking activity in the thalamus and activity in primary somatosensory cortex (S1) using extracellular electrophysiology and genetically encoded voltage imaging. Thalamic hyperpolarization significantly enhanced thalamic sensory-evoked bursting; however, surprisingly, the S1 cortical response was not amplified, but instead, timing precision was significantly increased, spatial activation more focused, and there was an increased synchronization of cortical inhibitory neurons. A thalamocortical network model implicates the modulation of precise timing of feedforward thalamic population spiking, presenting a highly sensitive, timing-based gating of sensory signaling to the cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.