Evidence map›Paper›PMID 35803238›Full record

ArticleStructure (London, England : 1993)2022

Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed.

W Scott Moye-Rowley

Open access · greenAbstract readComment
In one paragraph

Article in Structure (London, England : 1993), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

W Scott Moye-RowleyDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. Electronic address: scott-moye-rowley@uiowa.edu.
University of Iowa · US

Funding

Elevated gene transcription of the cyp51A gene is essential for azole drug resistance in Aspergillus fumigatusR01AI143198 · NIAID · UNIVERSITY OF IOWA · PI W Scott Moye-Rowley · 2019 to 2026
$3.9M
NIAID NIH HHS R01 AI143198
6 · The paper itself

Abstract

DNA recognition by the HapX transcription factor from Aspergillus species requires the presence of a heterotrimeric DNA-binding protein called the CCAAT-binding complex (CBC). In this issue of Structure, Huber and colleagues illuminate the structural basis for the multivalent binding of the CBC, HapX, and the DNA target site.

Indexed as

CCAAT-Binding FactorFungal ProteinsCarrier ProteinsDNATranscription FactorsCarrier ProteinsCCAAT-Binding FactorDNAFungal ProteinsTranscription Factors

Identifiers

PMID35803238
PMCPMC9830593
OpenAlexW4284882453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.