Evidence map›Paper›PMID 35802596›Full record

ArticleCancer immunology research2022

Direct T-cell Presentation by cDC1: The Key Feature for Cancer Vaccine Success?

Margaux Hubert, Christophe Caux, Jenny Valladeau-Guilemond

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Cancer immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Margaux HubertUniversité Claude Bernard Lyon 1, Inserm U1052, CNRS 5286, Cancer Research Center of Lyon, Lyon, France.ORCID 0000-0003-2584-6494
Christophe CauxUniversité Claude Bernard Lyon 1, Inserm U1052, CNRS 5286, Cancer Research Center of Lyon, Lyon, France.ORCID 0000-0003-2438-833X
Jenny Valladeau-GuilemondUniversité Claude Bernard Lyon 1, Inserm U1052, CNRS 5286, Cancer Research Center of Lyon, Lyon, France.ORCID 0000-0003-4160-8867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Cancer Immunology Research, Ferris and colleagues demonstrate that type 1 conventional DC (cDC1) vaccines drive tumor rejection through direct antigen presentation, without the need of endogenous cDC1. This suggests that cDC1-based vaccines could represent an optimal strategy to induce antitumor immunity in patients. See related article by Ferris et al., p. 920 (7) .

Indexed as

Cancer VaccinesNeoplasmsAntigen PresentationDendritic CellsHumansT-LymphocytesCancer Vaccines

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.