Evidence map›Paper›PMID 35802557›Full record

Observational studyPloS one2022

Impact of rigid gas-permeable contact lens on keratometric indices and corneal thickness of keratoconus eyes examined with anterior segment optical coherence tomography.

Kaho Akiyama, Takashi Ono, Hitoha Ishii, Lily Wei Chen, Kohdai Kitamoto, Tetsuya Toyono, Junko Yoshida, Makoto Aihara, Takashi Miyai

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kaho AkiyamaDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Takashi OnoDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Hitoha IshiiDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Lily Wei ChenDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Kohdai KitamotoDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Tetsuya ToyonoDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Junko YoshidaDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Makoto AiharaDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Takashi MiyaiDepartment of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.ORCID 0000-0001-5286-8272
University of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PURPOSE/

aimDetecting keratoconus (KC) progression helps determine the surgical indication for corneal cross-linking (CXL). This retrospective observational study aimed to examine changes in keratometric indices and corneal thickness in patients with KC who used rigid gas-permeable (RGP) contact lenses. MATERIALS AND

methodsThis study involved 31 eyes (31 patients) diagnosed with KC. No patient had used RGP or any other type of contact lenses for at least 1 month. Corneal topographic data were obtained using three-dimensional anterior segment optical coherence tomography before and after >1 month of RGP lens use.

resultsThe average and maximum keratometry values changed after using an RGP lens (-1.05 ± 1.92 D, p < 0.01 and -1.65 ± 4.20 D, p = 0.04, respectively); the spherical component of the anterior corneal surface became significantly smaller (p = 0.02). No change was observed in the central or thinnest corneal thickness values. Keratometric changes were greater in eyes with severe KC than in those with moderate KC (p = 0.014).

conclusionsKeratometry and spherical components of the anterior corneal surface values decreased after RGP lens use; keratometric changes were greater in eyes with severe KC than in those with moderate KC. Corneal progression indices, including corneal thickness, posterior keratometry, and irregular astigmatism values, mostly remained unchanged. It is important to consider these findings when evaluating corneal topography of KC and preparing CXL.

Indexed as

Contact LensesKeratoconusCorneaCorneal TopographyHumansTomography, Optical Coherence

Identifiers

PMID35802557
PMCPMC9269451
OpenAlexW4284973617

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.