ReviewThe journal of physical chemistry letters2022
Dynamical Signatures of Multifunnel Energy Landscapes.
Review in The journal of physical chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Energy Landscape and Kinetic Analysis of Molecular Dynamics Simulations for Intrinsically Disordered Proteins.The journal of physical chemistry. B · 2025Article
- Energy Landscapes of Model Knotted Polymers.Journal of chemical theory and computation · 2025Article
- Investigation into the effect of phenylalanine gating on anaerobic haem breakdown using the energy landscape approach.Protein science : a publication of the Protein Society · 2025Article
- Design principles for energy transfer in the photosystem II supercomplex from kinetic transition networks.Nature communications · 2024Article
- An encompassed representation of timescale hierarchies in first-order reaction network.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Analysing ill-conditioned Markov chains.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023Article
- Energy landscapes of Aβ monomers are sculpted in accordance with Ostwald's rule of stages.Science advances · 2023Article
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Authors and funding
1 author.
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Abstract
Multifunctional systems, such as molecular switches, exhibit multifunnel energy landscapes associated with the alternative functional states. In this contribution the multifunnel organization is decoded from dynamical signatures in the first passage time distribution between reactants and products. Characteristic relaxation rates are revealed by analyzing the kinetics as a function of the observation time scale, which scans the underlying distribution. Extracting the corresponding dynamical signatures provides direct insight into the organization of the molecular energy landscape, which will facilitate a rational design of target functionality. Examples are illustrated for multifunnel landscapes in biomolecular systems and an atomic cluster.
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