Evidence map›Paper›PMID 35801668›Full record

ArticleBioconjugate chemistry2022

Toward Bifunctional Chelators for Thallium-201 for Use in Nuclear Medicine.

Alex Rigby, George Firth, Charlotte Rivas, Truc Pham, Jana Kim, Andreas Phanopoulos, Luke Wharton, Aidan Ingham, Lily Li, Michelle T Ma and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Alex RigbySchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0003-2221-1602
George FirthSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0003-1603-5067
Charlotte RivasSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Truc PhamSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Jana KimSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Andreas PhanopoulosDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, United Kingdom.
Luke WhartonMedicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.ORCID 0000-0002-0636-8741
Aidan InghamMedicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.
Lily LiMedicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.
Michelle T MaSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0002-3349-7346
Chris OrvigMedicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.ORCID 0000-0002-2830-5493
Philip J BlowerSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0001-6290-1590
Samantha Y A TerrySchool of Biomedical Engineering and Imaging Sciences, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Vincenzo AbbateSchool of Cancer & Pharmaceutical Sciences, King's College London, Franklin-Wilkins Building, Stamford Street, London SE1 9NH, United Kingdom.ORCID 0000-0002-3300-0520
St Thomas' Hospital · GBTRIUMF · CAImperial College London · GBKing's College London · GBUniversity of British Columbia · CA

Funding

Cancer Research UK 24959Cancer Research UK C63178/A24959Wellcome TrustWellcome Trust 203148/Z/16/Z
6 · The paper itself

Abstract

Auger electron therapy exploits the cytotoxicity of low-energy electrons emitted during radioactive decay that travel very short distances (typically <1 μm).

Indexed as

Nuclear MedicineProstatic NeoplasmsAnimalsAntigens, SurfaceCell Line, TumorChelating AgentsGlutamate Carboxypeptidase IIHumansMaleMicePentetic AcidRadiopharmaceuticalsThallium RadioisotopesTissue DistributionAntigens, SurfaceChelating AgentsGlutamate Carboxypeptidase IIPentetic AcidRadiopharmaceuticalsThallium-201Thallium Radioisotopes

Identifiers

PMID35801668
PMCPMC9305974
OpenAlexW4284896194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.