Evidence map›Paper›PMID 35801660›Full record

ArticleJournal of applied microbiology2022

Assessment of humoral immune response to two mRNA SARS-CoV-2 vaccines (Moderna and Pfizer) in healthcare workers fully vaccinated with and without a history of previous infection.

Laura Serrano, Sonia Algarate, Beatriz Herrero-Cortina, Jessica Bueno, María T González-Barriga, María Ducons, Jesica Montero-Marco, Beatriz Acha, Ana Taboada, Pilar Sanz-Burillo and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Laura SerranoOccupational Health Unit, Lozano Blesa University Hospital, Zaragoza, Spain.
Sonia AlgarateMicrobiology Department, Lozano Blesa University Hospital, Zaragoza, Spain.
Beatriz Herrero-CortinaInstitute for Health Research Aragón, Zaragoza, Spain.
Jessica BuenoMicrobiology Department, Lozano Blesa University Hospital, Zaragoza, Spain.
María T González-BarrigaOccupational Health Unit, Lozano Blesa University Hospital, Zaragoza, Spain.
María DuconsMicrobiology Department, Lozano Blesa University Hospital, Zaragoza, Spain.
Jesica Montero-MarcoInstitute for Health Research Aragón, Zaragoza, Spain.
Beatriz AchaOccupational Health Unit, Lozano Blesa University Hospital, Zaragoza, Spain.
Ana TaboadaOccupational Health Unit, Lozano Blesa University Hospital, Zaragoza, Spain.
Pilar Sanz-BurilloOccupational Health Unit, Lozano Blesa University Hospital, Zaragoza, Spain.
Cristina YusteOccupational Health Unit, Lozano Blesa University Hospital, Zaragoza, Spain.ORCID https://orcid.org/0000-0003-3667-523X
Rafael BenitoInstitute for Health Research Aragón, Zaragoza, Spain.ORCID https://orcid.org/0000-0001-5134-1006
RIPOVAC Study Group
Hospital Clínico Universitario Lozano Blesa · ESUniversidad de Zaragoza · ESUniversidad San Jorge · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPresence of anti-S1 region of SARS-CoV-2 spike protein was analysed, at two and eight months, in 477 immunocompetent healthcare workers in Zaragoza, Spain, vaccinated with mRNA-1273 (Moderna) or BNT162b2 (Pfizer). METHODS AND

resultsAntibody analysis was performed with Alinity i System (Abbott). At 2 months, 100% of vaccinated had anti-S1 IgG (mean = 13,285 AU ml

conclusionAt 2 and 8 months after vaccination, IgG response persists with both vaccines but with important decrease which suggests the need for revaccination. SIGNIFICANCE AND IMPACT OF STUDY: The study contributes to know the immune status after vaccination with two of more used anti-SARS-CoV-2 vaccines. This knowledge is important for establishing the best vaccination strategy.

Indexed as

COVID-19COVID-19 VaccinesImmunity, Humoral2019-nCoV Vaccine mRNA-1273Antibodies, ViralBNT162 VaccineHealth PersonnelHumansImmunoglobulin GSARS-CoV-2SpainSpike Glycoprotein, CoronavirusVaccination2019-nCoV Vaccine mRNA-1273Antibodies, ViralBNT162 VaccineCOVID-19 VaccinesImmunoglobulin GSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2anti-S IgG SARS-CoV-2healthcare workersimmune responseModernamRNA SARS-CoV-2 vaccinesPfizerpost-vaccinationRIPOVAC

Identifiers

PMID35801660
PMCPMC9350023
OpenAlexW4284884371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.