Evidence map›Paper›PMID 35801410›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics - synthesis and properties.

Joanna Stefaniak, Michał G Nowak, Marek Wojciechowski, Sławomir Milewski, Andrzej S Skwarecki

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Synthesis,RSC medicinal chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joanna StefaniakDepartment of Organic Chemistry and BioTechMed Center, Gdańsk University of Technology, Gdańsk, Poland.
Michał G NowakDepartment of Organic Chemistry and BioTechMed Center, Gdańsk University of Technology, Gdańsk, Poland.
Marek WojciechowskiDepartment of Pharmaceutical Technology and Biochemistry and BioTechMed Center, Gdańsk University of Technology, Gdańsk, Poland.
Sławomir MilewskiDepartment of Pharmaceutical Technology and Biochemistry and BioTechMed Center, Gdańsk University of Technology, Gdańsk, Poland.
Andrzej S SkwareckiDepartment of Pharmaceutical Technology and Biochemistry and BioTechMed Center, Gdańsk University of Technology, Gdańsk, Poland.
Gdańsk University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucosamine-6-phosphate synthase (GlcN-6-P synthase) is known as a promising target for antimicrobial agents and antidiabetics. Several compounds of natural or synthetic origin have been identified as inhibitors of this enzyme. This set comprises highly selective l-glutamine, amino sugar phosphate or transition state intermediate

Indexed as

Anti-Infective AgentsGlutamine-Fructose-6-Phosphate Transaminase (Isomerizing)Enzyme InhibitorsHypoglycemic AgentsMolecular Docking SimulationAnti-Infective AgentsEnzyme InhibitorsGlutamine-Fructose-6-Phosphate Transaminase (Isomerizing)Hypoglycemic Agentsantibacterial agentsantifungal agentsdiabetesdrug synthesisGlucosamine-6-phosphate synthase

Identifiers

PMID35801410
PMCPMC9272926
OpenAlexW4284898421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.