Evidence map›Paper›PMID 35801048›Full record

ArticleWorld journal of clinical cases2022

Solitary primary pulmonary synovial sarcoma: A case report.

Wei-Wei He, Zhi-Xin Huang, Wen-Jing Wang, Yu-Lei Li, Qiu-Yuan Xia, Yong-Bin Qiu, Yi Shi, Hui-Ming Sun

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wei-Wei HeDepartment of Respiratory and Critical Care Medicine, Nanjing Yimin Hospital, Nanjing 210000, Jiangsu Province, China.
Zhi-Xin HuangDepartment of Respiratory and Critical Care Medicine, Nanjing Yimin Hospital, Nanjing 210000, Jiangsu Province, China.
Wen-Jing WangDepartment of Respiratory and Critical Care Medicine, Nanjing Yimin Hospital, Nanjing 210000, Jiangsu Province, China.
Yu-Lei LiDepartment of Respiratory and Critical Care Medicine, Nanjing Yimin Hospital, Nanjing 210000, Jiangsu Province, China.
Qiu-Yuan XiaDepartment of Pathology, Jinling Hospital, Nanjing 210002, Jiangsu Province, China.
Yong-Bin QiuDepartment of Respiratory and Critical Care Medicine, Nanjing Yimin Hospital, Nanjing 210000, Jiangsu Province, China.
Yi ShiDepartment of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing 210002, Jiangsu Province, China.
Hui-Ming SunDepartment of Respiratory and Critical Care Medicine, Nanjing Yimin Hospital, Nanjing 210000, Jiangsu Province, China. shm-icu@163.com.
Jiangsu Province Hospital · CNHebei Yiling Hospital · CNJinling Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSynovial sarcoma (SS) is an uncommon and highly malignant soft tissue sarcoma in the clinic, with primary pulmonary SS (PPSS) being extremely rare. Here, we describe the clinical characteristics, diagnosis, and treatment of a solitary PPSS case confirmed CASE SUMMARY: A 33-year-old man was admitted because of intermittent coughing and hemoptysis for one month, with lung shadows observed for two years. Whole-body positron emission tomography-computed tomography (PET-CT) revealed a solitary mass in the upper lobe of the right lung, with uneven radioactivity uptake and a maximum standardized uptake value of 5.6. The greyish-yellow specimen obtained following thoracoscopic resection was covered with small multi-nodulated structures and consisted of soft tissue. Hematoxylin and eosin staining revealed spindle-shaped malignant tumor cells. Immunohistochemistry indicated these tumor cells were CD99 and BCL-2-positive. Furthermore, the FISH test revealed synovial sarcoma translocation genetic reassortment, which confirmed the diagnosis of SS.

conclusionPPSS is extremely rare and tends to be misdiagnosed as many primary pulmonary diseases. PET-CT, histologic analysis, and FISH tests can be used to differentiate PPSS from other diseases. Surgical resection is regularly recommended for the treatment of solitary PPSS and is helpful for improving the prognosis.

Indexed as

Case reportFluorescence in situ hybridizationPositron emission tomography-computed tomographyPrimary pulmonary synovial sarcomaSolitary pulmonary noduleSpindle cellsSynovial sarcoma translocation

Identifiers

PMID35801048
PMCPMC9198894
OpenAlexW4281294401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.