Evidence map›Paper›PMID 35800350›Full record

ArticleCardiovascular diagnosis and therapy2022

AKT-mTOR signaling-mediated rescue of

Jian Zhuo, Haihua Geng, Xiaohui Wu, Mengkang Fan, Hongzhuan Sheng, Jian Yao

Open access · diamondAbstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  8. Status of βReviews in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jian Zhuo *Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Haihua Geng *Department of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Xiaohui WuDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Mengkang FanDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Hongzhuan ShengDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Jian YaoDepartment of Histology and Embryology, Medical School of Nantong University, Nantong, China.
Affiliated Hospital of Nantong University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Protein kinase AMP-activated non-catalytic subunit gamma 2 gene ( Methods: We constructed a fluorescently labeled adenovirus carrying the wild-type or R302Q mutant of the Results: Overexpression of Conclusions: The current study not only determined the mechanism regulating HCM induced by

Indexed as

hypertrophic cardiomyopathy (HCM)PRKAG2R302Qβ-adrenergic receptor blocker (β-AR blocker)

Identifiers

PMID35800350
PMCPMC9253164
OpenAlexW4284963758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.