ArticleFrontiers in bioengineering and biotechnology2022
Computer-Aided Design of α-L-Rhamnosidase to Increase the Synthesis Efficiency of Icariside I.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Engineering galactoside acetyltransferase for enhanced hesperetin-7-O-glucoside bioavailability.Applied microbiology and biotechnology · 2026Article
- An Organic Solvent-Tolerant α-L-Rhamnosidase fromMolecules (Basel, Switzerland) · 2025Article
- Natural anti-cancer products: insights from herbal medicine.Chinese medicine · 2025Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Icariside I, the glycosylation product of icaritin, is a novel effective anti-cancer agent with immunological anti-tumor activity. However, very limited natural icariside I content hinders its direct extraction from plants. Therefore, we employed a computer-aided protein design strategy to improve the catalytic efficiency and substrate specificity of the α-L-rhamnosidase from
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Registered trials
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