Evidence map›Paper›PMID 35800291›Full record

ArticleVascular health and risk management2022

Are Any Changes in Carotid Intima-Media Thickness Associated with Cardiometabolic Risk Among Adult Bantu Central African Hypertensive Patients from Monkole and Biamba Marie Mutombo Hospitals?

Stéphane Yanda Tongo, Benjamin Longo-Mbenza, Antoine Molua Aundu, Raoul Gombet, Jean Robert Makulo Risasi, Christian Kisoka Lusunsi, Héritier Mawalala Malengele, Augustin Nge Okwe

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Stéphane Yanda TongoRadiology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo.
Benjamin Longo-MbenzaCardiology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo.ORCID 0000-0002-5164-6296
Antoine Molua AunduRadiology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo.
Raoul GombetMarien Ngouabi University, Brazzaville, Democratic Republic of Congo.
Jean Robert Makulo RisasiNephrology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo.ORCID 0000-0001-5517-3281
Christian Kisoka LusunsiDepartment of Public Health, Lomo University for Research, Kinshasa, Democratic Republic of Congo.ORCID 0000-0002-0576-841X
Héritier Mawalala MalengeleRadiology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo.
Augustin Nge OkweDepartment of Public Health, Lomo University for Research, Kinshasa, Democratic Republic of Congo.
University of Kinshasa · CDMarien Ngouabi University · CG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several classic/traditional risk factors are associated with intima-media thickness (IMT), a novel risk of cardio metabolic risk (CMR) in the literature but not in Kinshasa, a megacity prone to CMR. Thus, the objective of this study was to evaluate potential correlations between inflammation, kidney function, psychological stress, hemodynamics, and changes in IMT. Methods: This cross-sectional study was carried out between 2018 and 2021 within Monkole and Biamba Marie Mutombo Hospitals, respectively, and randomly selected from 10 health structures from East and West of Kinshasa, Capital of Democratic Republic Congo (DRC). A random sample of adult hypertensive Bantu Central Africans was examined after bivariate correlations and multiple linear regression. Results: Out of 280 patients with 140 men and 140 women aged 62 ± 11 years, the mean carotid intima-media thickness (CIMT) was 1.06 ± 0.5 mm and 73% (n = 204) patients had uncontrolled hypertension. After controlling for confounders, 52.9% variations (R2) of CIMT were independently and significantly (P = 0.037) predicted by CRP, 24-hour proteinuria, urinary albumin/creatinine ratio, duration of hypertension, heart rate, hip circumference, and psychological stress with Equation Y = 0.717 + 0.87 × CRP + 0.02 × 24 H - proteinuria + 0.005 × urinary albumin/creatinine ratio + 0.05 × duration of hypertension + 0.001 × heart rate + 0.006 × hip circumference + 0.017 × psychological stress. Conclusion: There is an urgent need to control inflammation, impaired renal function, cardiac rhythm, peripheral obesity, longer duration of hypertension management, and stress, which are emerging as specific novel determinants of the subclinical atherosclerosis for those Bantu Central African hypertensive patients.

Indexed as

Carotid Intima-Media ThicknessHypertensionAdultAlbuminsCreatinineCross-Sectional StudiesDemocratic Republic of the CongoFemaleHospitalsHumansInflammationMaleProteinuriaRisk FactorsAlbuminsCreatininecarotid intima–media thicknessCentral Africanssubclinical atherosclerosis

Identifiers

PMID35800291
PMCPMC9255902
OpenAlexW4283718789

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.