Evidence map›Paper›PMID 35800227›Full record

ArticleContrast media & molecular imaging2022

The Prognostic Assessment of CDC20 in Patients with Renal Clear Cell Carcinoma and Its Relationship with Body Immunity.

Jiaqi Shi, Yinhao Chen, Xiameng Gu, Xuerong Wang, Jing Liu, Xiaolan Chen

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. CDC20 promotes radioresistance of prostate cancer by activating Twist1 expression.Apoptosis : an international journal on programmed cell death · 2023
    Article
  7. Frontiers in oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiaqi ShiDepartment of Nephrology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.ORCID 0000-0002-3948-7245
Yinhao ChenNantong University School of Medicine, Nantong 226001, Jiangsu, China.ORCID 0000-0002-0324-4700
Xiameng GuDepartment of Nephrology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Xuerong WangDepartment of Nephrology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Jing LiuDepartment of Nephrology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Xiaolan ChenDepartment of Nephrology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.ORCID 0000-0002-1043-1889
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article analyzes the relationship between cell division cycle (CDC20) molecules and oncology outcomes in patients with renal clear cell carcinoma (KIRC). CDC20 appears to act as a regulatory protein interacting with many other proteins at multiple points in the cycle. The RNA sequencing data and corresponding clinical information of CDC20 molecules were obtained from The Cancer Genome Atlas (TCGA) database. The expression of CDC20 in kidney renal clear cell carcinoma tissue and adjacent normal tissue was detected by immunohistochemical methods. Logistic analysis was performed to analyze the role of CDC20 in the clinicopathological characteristics and prognosis of KIRC. Gene Set Enrichment Analysis (GSEA) was used to identify the signal pathways which were related to CDC20. Independent prognostic factors were evaluated using univariate and multivariate Cox regression analysis. A nomogram involved in CDC20 expression and clinicopathological variables was conducted to predict overall survival (OS) in KIRC patients at 1, 3, and 5 years. Furthermore, the relation between CDC20 and immunity was also studied. Our results showed that CDC20 was upregulated in kidney renal clear cell carcinoma tissues, accompanying shorter OS (all

Indexed as

Carcinoma, Renal CellKidney NeoplasmsBiomarkers, TumorCdc20 ProteinsHumansImmunohistochemistryPrognosisTumor MicroenvironmentBiomarkers, TumorCDC20 protein, humanCdc20 Proteins

Identifiers

PMID35800227
PMCPMC9200543
OpenAlexW4285048442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.