ArticleCureus2022
Pregnancy-Associated Atypical Hemolytic Uremic Syndrome and Life-Long Kidney Failure.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 2 citations in OpenAlex.
- A case report of postpartum hemolytic uremic syndrome.American journal of translational research · 2026Article
- Multidisciplinary management of concurrent postpartum eclampsia, HELLP syndrome, ruptured hepatic subcapsular hematoma, and atypical hemolytic uremic syndrome: a case report.BMC pregnancy and childbirth · 2025Article
- Atypical hemolytic uremic syndrome associated with pregnancy: A case report.Medicine internationalArticle
- Ravulizumab in treatment-naïve patients with atypical hemolytic uremic syndrome: a real-world case series.Drug target insightsArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by a triad of thrombocytopenia, thrombotic microangiopathy, and acute renal failure. The background pathogenesis of aHUS stems from mutations in the genes of the complement cascade. However, certain circumstances including normal physiological conditions such as pregnancy, environmental factors, or triggers, can activate genetically predisposed individuals and lead to aHUS. We present a case of a young female who presented with acute renal failure and later was diagnosed with aHUS. Possible potential triggers were investigated, and it is believed that pregnancy was associated with the development of aHUS in this young genetically predisposed female leading to life-long acute renal failure. This case highlights a unique case of a devastating systemic disease triggered by a normal physiological phenomenon. Moreover, it reiterates the importance of early diagnosis and how it is imperative to proceed to treatment promptly to prevent chronic renal failure. Further reporting of cases is warranted to monitor the incidence and improve prognostic outcomes in patients with aHUS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.