ReviewCureus2022
Normothermic Regional Perfusion is an Emerging Cost-Effective Alternative in Donation After Circulatory Death (DCD) in Heart Transplantation.
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Outcomes of donation after circulatory death heart transplant using normothermic regional perfusion: a systematic review and meta-analysis.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Pooled it
- Global transplantation: Lessons from organ transplantation organizations worldwide.World journal of transplantation · 2025Review
- Outcomes of Donation After Circulatory Death Heart Transplantation Using Normothermic Regional Perfusion.Annals of thoracic surgery short reports · 2025Article
- Challenges and opportunities in organ donation after circulatory death.Journal of internal medicine · 2025Review
- Donation after circulatory death transplantation: a systematic review and meta-analysis of outcomes and methods of donation.Annals of cardiothoracic surgery · 2025Article
- Adult cardiac transplantation utilizing donors after circulatory death.Annals of cardiothoracic surgery · 2024Review
- Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment.Journal of visualized experiments : JoVE · 2024Article
- Revolutionizing Donor Heart Procurement: Innovations and Future Directions for Enhanced Transplantation Outcomes.Journal of cardiovascular development and disease · 2024Review
- European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant.Transplant international : official journal of the European Society for Organ Transplantation · 2024Review
- Donor and recipient risk factors for the development of primary graft dysfunction following lung transplantation.Frontiers in immunology · 2024Review
- Novel portable hypothermic machine perfusion preservation device enhances cardiac viability of donated human hearts.Frontiers in cardiovascular medicine · 2024Article
- Pediatric heart transplantation from donation after circulatory death using normothermic regional perfusion and cold storage from a distant donor: First US experience.JTCVS techniques · 2023Article
- Normothermic Regional Perfusion Can Improve Both Utilization and Outcomes in DCD Liver, Kidney, and Pancreas Transplantation.Transplantation direct · 2023Article
- Thoracic organ machine perfusion: A review of concepts with a focus on reconditioning therapies.Frontiers in transplantation · 2023Review
- Dilemmas concerning heart procurement in controlled donation after circulatory death.Frontiers in cardiovascular medicine · 2023Review
- Swedish Intensive Care Nurses' Knowledge, Attitudes, and Views on Donation After Circulatory Death Before a National Implementation.SAGE open nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In donation after circulatory death (DCD) organ transplantation, normothermic regional perfusion (NRP) restores oxygenated blood flow following cardiac arrest and reverses warm ischemia. Recently, NRP has also been used to help recover DCD hearts in addition to the abdominal organs. While DCD donation has increased the number of abdominal organs and lungs pool, it has not been able to increase the number of heart transplants, despite the fact that it has the potential to increase the number of heart transplants by 15-30%. Thoracoabdominal normothermic regional perfusion makes heart transplantation feasible and permits assessing heart function before an organ procurement without affecting the preservation of abdominal organs. NRP can be used in two ways for DCD donor heart transplants: normothermic regional perfusion followed by machine perfusion (NRP-MP) and normothermic regional perfusion followed by static cold storage (NRP-SCS). Normothermic regional perfusion is an emerging technology, a cost-effective alternative in donation after circulatory death (DCD), and will increase the pool of donors in heart transplantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.