Evidence map›Paper›PMID 35800110›Full record

ArticleIJU case reports2022

Bone marrow metastasis in a patient with non-seminomatous testicular germ cell tumor.

Takashi Ueda, Ippei Takada, Teruki Shimizu, Saya Ito, Atsuko Fujihara, Takumi Shiraishi, Terukazu Nakamura, Osamu Ukimura

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Takashi UedaDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.ORCID https://orcid.org/0000-0001-7771-1407
Ippei TakadaDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.
Teruki ShimizuDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.ORCID https://orcid.org/0000-0002-7470-8840
Saya ItoDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.
Atsuko FujiharaDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.
Takumi ShiraishiDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.
Terukazu NakamuraDepartment of Urology Saiseikai Suita Hospital Suita Kyoto Japan.
Osamu UkimuraDepartment of Urology Kyoto Prefectural University of Medicine Kyoto City Kyoto Japan.
Kyoto Prefectural University of Medicine · JPSaiseikai Suita Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Metastasis to the bone marrow is rare in testicular germ cell tumor patients. We report a case of a patient with a non-seminomatous testicular germ cell tumor who presented with bone marrow metastases after intensive chemotherapy. Case presentation: A 36-year-old man was admitted to the hospital with pancytopenia. Previously, he had received intensive care for an advanced left testicular germ cell tumor. Although multidisciplinary treatments including several regimens of salvage chemotherapy, desperation retroperitoneal lymph node dissection, and focal radiotherapy were performed, the serum tumor marker alfa-fetoprotein was not normalized and there were no findings of relapse by several imaging modalities. Bone marrow aspirate, conducted to diagnose a cause of pancytopenia, revealed metastatic germ cell tumors in the bone marrow. Conclusion: Bone marrow metastasis should be considered as a differential diagnosis in patients with germ cell tumors whose serum tumor makers are not normalized without any radiographic finding of recurrence.

Indexed as

AFPbone marrow metastasisdesperation RPLNDsalvage chemotherapytesticular germ cell tumor

Identifiers

PMID35800110
PMCPMC9249660
OpenAlexW4223485225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.