Evidence map›Paper›PMID 35799814›Full record

ReviewChemical science2022

Halogen bonding and chalcogen bonding mediated sensing.

Robert Hein, Paul D Beer

Abstract readReview
In one paragraph

Review in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Supramolecular Chalcogen-Bonded Shape Memory Actuators.Angewandte Chemie (International ed. in English) · 2025
    Article
  6. Highly Enantioselective Organocatalysis with Bidentate Halogen Bond Donors.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Solvent effects in anion recognition.Nature reviews. Chemistry · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Halogen Bonding Involving Isomeric Isocyanide/Nitrile Groups.International journal of molecular sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert HeinDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford Mansfield Road Oxford OX1 3TA UK paul.beer@chem.ox.ac.uk.ORCID https://orcid.org/0000-0001-8567-0924
Paul D BeerDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford Mansfield Road Oxford OX1 3TA UK paul.beer@chem.ox.ac.uk.ORCID https://orcid.org/0000-0003-0810-9716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sigma-hole interactions, in particular halogen bonding (XB) and chalcogen bonding (ChB), have become indispensable tools in supramolecular chemistry, with wide-ranging applications in crystal engineering, catalysis and materials chemistry as well as anion recognition, transport and sensing. The latter has very rapidly developed in recent years and is becoming a mature research area in its own right. This can be attributed to the numerous advantages sigma-hole interactions imbue in sensor design, in particular high degrees of selectivity, sensitivity and the capability for sensing in aqueous media. Herein, we provide the first detailed overview of all developments in the field of XB and ChB mediated sensing, in particular the detection of anions but also neutral (gaseous) Lewis bases. This includes a wide range of optical colorimetric and luminescent sensors as well as an array of electrochemical sensors, most notably redox-active host systems. In addition, we discuss a range of other sensor designs, including capacitive sensors and chemiresistors, and provide a detailed overview and outlook for future fundamental developments in the field. Importantly the sensing concepts and methodologies described herein for the XB and ChB mediated sensing of anions, are generically applicable for the development of supramolecular receptors and sensors in general, including those for cations and neutral molecules employing a wide array of non-covalent interactions. As such we believe this review to be a useful guide to both the supramolecular and general chemistry community with interests in the fields of host-guest recognition and small molecule sensing. Moreover, we also highlight the need for a broader integration of supramolecular chemistry, analytical chemistry, synthetic chemistry and materials science in the development of the next generation of potent sensors.

Identifiers

PMID35799814
PMCPMC9214886

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.