Evidence map›Paper›PMID 35799808›Full record

ArticleChemical science2022

An unexpected all-metal aromatic tetranuclear silver cluster in human copper chaperone Atox1.

Xiuxiu Wang, Zong-Chang Han, Wei Wei, Hanshi Hu, Pengfei Li, Peiqing Sun, Xiangzhi Liu, Zhijia Lv, Feng Wang, Yi Cao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiuxiu WangState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 China jingzhao@nju.edu.cn.
Zong-Chang HanDepartment of Chemistry and Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Tsinghua University Beijing 100084 China.
Wei WeiState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 China jingzhao@nju.edu.cn.ORCID https://orcid.org/0000-0003-0845-0527
Hanshi HuDepartment of Chemistry and Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Tsinghua University Beijing 100084 China.ORCID https://orcid.org/0000-0001-9508-1920
Pengfei LiNational Laboratory of Solid State Microstructure, Department of Physics, Nanjing University Nanjing 210023 China.
Peiqing SunState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 China jingzhao@nju.edu.cn.
Xiangzhi LiuSchool of Life Sciences, Nanjing University Nanjing 210023 China.
Zhijia LvElias James Corey Institute of Biomedical Research, Wuxi Biortus Biosciences Co., Ltd Jiangyin 214437 China.
Feng WangElias James Corey Institute of Biomedical Research, Wuxi Biortus Biosciences Co., Ltd Jiangyin 214437 China.
Yi CaoNational Laboratory of Solid State Microstructure, Department of Physics, Nanjing University Nanjing 210023 China.
Zijian GuoState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 China jingzhao@nju.edu.cn.ORCID https://orcid.org/0000-0003-4986-9308
Jun LiDepartment of Chemistry and Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Tsinghua University Beijing 100084 China.ORCID https://orcid.org/0000-0002-8456-3980
Jing ZhaoState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 China jingzhao@nju.edu.cn.ORCID https://orcid.org/0000-0001-5177-5699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal clusters, such as iron-sulfur clusters, play key roles in sustaining life and are intimately involved in the functions of metalloproteins. Herein we report the formation and crystal structure of a planar square tetranuclear silver cluster when silver ions were mixed with human copper chaperone Atox1. Quantum chemical studies reveal that two Ag 5s

Identifiers

PMID35799808
PMCPMC9214858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.