ArticleVeterinary research2022
Repeated cross-sectional sampling of pigs at slaughter indicates varying age of hepatitis E virus infection within and between pig farms.
Article in Veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Biosecurity measures reducingFrontiers in veterinary science · 2024Pooled it
- Zoonotic hepatitis E virus spreads through environmental routes in pig herds - A phylodynamic analysis.PLoS pathogens · 2025Article
- Article
- First evidence of hepatitis E virus in domestic pigs: a cross-sectional seroepidemiological study in the Bosnia and Herzegovina.Frontiers in veterinary science · 2025Article
- Utility of various genome lengths in diversity and evolution analyses of Hepatitis E virus.Virus research · 2024Article
- Detection of Hepatitis E Virus in Game Meat (Wild Boar) Supply Chain in Umbria Region, Central Italy.Foods (Basel, Switzerland) · 2024Article
- Biosecurity measures to control hepatitis E virus on European pig farms.Frontiers in veterinary science · 2024Article
- Development of an Ex Vivo Assay for Identification of Infectious Hepatitis E Virus in Different Kinds of Food Samples.Pathogens (Basel, Switzerland) · 2023Article
- Hepatitis E Virus (HEV) in Heavy Pigs in Slaughterhouses of Northern Italy: Investigation of Seroprevalence, Viraemia, and Faecal Shedding.Animals : an open access journal from MDPI · 2023Article
- Article
- Farm biosecurity measures to prevent hepatitis E virus infection in finishing pigs on endemically infected pig farms.One health (Amsterdam, Netherlands) · 2023Article
- Evaluation of Non-Invasive Sampling Methods for Detection of Hepatitis E Virus Infected Pigs in Pens.Microorganisms · 2023Article
- A Randomized Large-Scale Cross-Sectional Serological Survey of Hepatitis E Virus Infection in Belgian Pig Farms.Microorganisms · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Humans can become infected with hepatitis E virus (HEV) by consumption of undercooked pork. To reduce the burden of HEV in humans, mitigation on pig farms is needed. HEV is found on most pig farms globally, yet within-farm seroprevalence estimates vary considerably. Understanding of the underlying variation in infection dynamics within and between farms currently lacks. Therefore, we investigated HEV infection dynamics by sampling 1711 batches of slaughter pigs from 208 Dutch farms over an 8-month period. Four farm types, conventional, organic, and two types with strict focus on biosecurity, were included. Sera were tested individually with an anti-HEV antibody ELISA and pooled per batch with PCR. All farms delivered seropositive pigs to slaughter, yet batches (resembling farm compartments) had varying results. By combining PCR and ELISA results, infection moment and extent per batch could be classified as low transmission, early, intermediate or late. Cluster analysis of batch infection moments per farm resulted in four clusters with distinct infection patterns. Cluster 1 farms delivered almost exclusively PCR negative, ELISA positive batches to slaughter (PCR
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