Evidence map›Paper›PMID 35799202›Full record

ArticleCancer & metabolism2022

Likun Duan, Daniel E Cooper, Grace Scheidemantle, Jason W Locasale, David G Kirsch, Xiaojing Liu

Open access · goldAbstract read
In one paragraph

Article in Cancer & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. Effects of aging on glucose and lipid metabolism in mice.bioRxiv : the preprint server for biology · 2023
    Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Likun DuanDepartment of Molecular and Structural Biochemistry, NC State University, Raleigh, NC, 27695, USA.
Daniel E CooperDepartment of Radiation Oncology, Duke University School of Medicine, Durham, NC, 27708, USA.
Grace ScheidemantleDepartment of Molecular and Structural Biochemistry, NC State University, Raleigh, NC, 27695, USA.
Jason W LocasaleDepartment of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27708, USA.
David G KirschDepartment of Radiation Oncology, Duke University School of Medicine, Durham, NC, 27708, USA.
Xiaojing LiuDepartment of Molecular and Structural Biochemistry, NC State University, Raleigh, NC, 27695, USA. xliu68@ncsu.edu.ORCID http://orcid.org/0000-0002-4231-6017
Duke University · USNorth Carolina State University · US

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI Lee Zou · 1985 to 2026
$174.8M
Advancing Cancer Therapy through Ground Breaking Research in Radiation BiologyR35CA197616 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI David Guy Kirsch · 2016 to 2026
$10.7M
Training Grant In Radiation BiologyT32CA093240 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FREEMAN, MICHAEL L. · 2002 to 2016
$2.3M
Duke Cancer Institute Pilot Grant P30CA014236Foundation for the National Institutes of Health R35CA197616NCI NIH HHS P30 CA014236NCI NIH HHS R35 CA197616NCI NIH HHS T32 CA093240NIH HHS T32CA093240
6 · The paper itself

Abstract

background

methodsWe have performed [U-

resultsWe observed distinct enrichment patterns of tricarboxylic acid cycle intermediates in vivo and in vitro. As expected, citrate M + 2 or M + 4 was the dominant mass isotopologue in vitro. However, citrate M + 1 was unexpectedly the dominant isotopologue in mice receiving [U-

conclusionsAltogether, our results show that recycling of endogenous CO

Indexed as

13C tracingAnaplerotic metabolismCO2 recyclingHigh-resolution mass spectrometry

Identifiers

PMID35799202
PMCPMC9264524
OpenAlexW4284690212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.