Evidence map›Paper›PMID 35799132›Full record

ArticleBMC nephrology2022

Comparison of the prevalence of kidney disease by proteinuria and decreased estimated glomerular filtration rate determined using three creatinine-based equations among patients admitted on medical wards of Masaka Regional Referral Hospital in Uganda: a prospective study.

SSenabulya F Ronny, Nankabirwa I Joaniter, Kalyesubula Robert, Wandera Bonnie, Kirenga Bruce, Kayima James, Ocama Posiano, Bagasha Peace

Abstract read
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

SSenabulya F RonnyDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda. frssenna@gmail.com.
Nankabirwa I JoaniterDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda.
Kalyesubula RobertDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda.
Wandera BonnieMakerere NCD Training Program, Makerere Lung Institute, Kampala, Uganda.
Kirenga BruceDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda.
Kayima JamesDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda.
Ocama PosianoDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda.
Bagasha PeaceDepartment of Medicine, Makerere University College of Health Sciences, P.O.BOX 7062, Kampala, Uganda.

Funding

Training in noncommunicable diseases epidemiological, data science and Implementation Science research to strengthen evidence-based interventions, policy and control in Uganda.D43TW011401 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI Charles Batte, William Checkley · 2019 to 2026
$1.8M
FIC NIH HHS D43 TW011401
6 · The paper itself

Abstract

backgroundDespite estimated glomerular filtration rate (eGFR) being the best marker for kidney function, there are no studies in sub-Saharan Africa comparing the performance of various equations used to determine eGFR. We compared prevalence of kidney disease determined by proteinuria of ≥  + 1 and or kidney disease improving global outcomes (KDIGO) eGFR criteria of < 60 ml/minute/1.73m

methodsThis was a prospective study conducted among adult patients admitted on medical wards between September 2020 to March 2021. Spot urine samples were collected to assess for proteinuria and blood samples were collected to assess serum creatinine levels. Kidney disease was defined as proteinuria of ≥ 1 + on spot urine dipstick and or KDIGO eGFR criteria of < 60 ml/minute/1.73m

resultsAmong the 357 patients enrolled in the study, KDIGO eGFR criteria of < 60mls / minute determined using FAS and CKD-EPI 2009 without race factor equations and or proteinuria of ≥  + 1 showed the highest overall prevalence of kidney disease at 27.2%. Prevalence of confirmed CKD at 90 days was highest with proteinuria ≥  + 1 and or KDIGO eGFR criteria of < 60mls/min determined using CKD EPI 2009 without race factor Equation (15.1%).

conclusionsUse of KDIGO eGFR criteria of < 60mls / minute /1.73m

Indexed as

Renal Insufficiency, ChronicAdultCreatinineGlomerular Filtration RateHospitalsHumansPrevalenceProspective StudiesProteinuriaReferral and ConsultationUgandaCreatinineComparison of prevalence of kidney diseaseEstimated glomerular filtration rate equationsKidney disease

Identifiers

PMID35799132
PMCPMC9264612

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.