Evidence map›Paper›PMID 35799104›Full record

ArticleBMC cardiovascular disorders2022

Validation and derivation of short-term prognostic risk score in acute decompensated heart failure in China.

Hong-Liang Zhao, Xiao-Li Gao, Ying-Hua Liu, Sen-Lin Li, Qi Zhang, Wei-Chao Shan, Qun Zheng, Jiang Zhou, Yong-Zheng Liu, Li Liu and 8 more

Open access · goldAbstract readValidation Study
In one paragraph

Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Ventricular arrhythmias in acute heart failure: a clinical consensus statement of the Association for Acute CardioVascular Care, the European Heart Rhythm Association, and the Heart Failure Association of the European Society of Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  8. Article
  9. Article
  10. Prognostic Clinical Phenotypes of Patients with Acute Decompensated Heart Failure.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Hong-Liang Zhao *First Division, Department of Cardiology, The Second Hospital of Hebei Medical University, Heping West Road No. 215, Shijiazhuang, 050000, Hebei province, China.ORCID 0000-0002-1331-8515
Xiao-Li Gao *Department of Cardiology, Huabei Petroleum Administration Bureau General Hospital, Renqiu, 062552, Hebei Province, China.ORCID 0000-0002-3785-5649
Ying-Hua LiuDepartment of Cardiology, Huabei Petroleum Administration Bureau General Hospital, Renqiu, 062552, Hebei Province, China.ORCID 0000-0002-5406-3360
Sen-Lin LiDepartment of Cardiology, Zhangjiakou First Hospital, Zhangjiakou, 075000, Hebei Province, China.ORCID 0000-0001-7686-0494
Qi ZhangDepartment of Cardiology, Baoding First Central Hospital, Baoding, 071000, Hebei Province, China.ORCID 0000-0002-1260-0869
Wei-Chao ShanDepartment of Cardiology, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei Province, China.ORCID 0000-0001-5014-7586
Qun ZhengDepartment of Cardiology, Hengshui People's Hospital, Hengshui, 053000, Hebei Province, China.ORCID 0000-0003-0820-9151
Jiang ZhouDepartment of Cardiology, Chengde Central Hospital, Chengde, 067024, Hebei Province, China.ORCID 0000-0002-8040-9230
Yong-Zheng LiuDepartment of Cardiology, Qinhuangdao First Hospital, Qinhuangdao, 066099, Hebei Province, China.ORCID 0000-0002-4450-8100
Li LiuDepartment of Cardiology, Qinhuangdao First Hospital, Qinhuangdao, 066099, Hebei Province, China.ORCID 0000-0002-5680-3449
Nan GuoDepartment of Cardiology, Cangzhou Central Hospital, Cangzhou, 061011, Hebei Province, China.ORCID 0000-0003-1191-8653
Hong-Sen TianDepartment of Cardiology, Handan Central Hospital, Handan, 056000, Hebei Province, China.ORCID 0000-0001-6841-3627
Qing-Min WeiDepartment of Cardiology, Xingtai People's Hospital, Xingtai, 054001, Hebei Province, China.ORCID 0000-0003-2503-6651
Xi-Tian HuDepartment of Cardiology, Shijiazhuang People's Hospital, Shijiazhuang, 050011, Hebei Province, China.ORCID 0000-0002-6763-0424
Ying-Kai CuiDepartment of Cardiology, The 252nd Hospital of People's Liberation Army, Baoding, 071000, Hebei Province, China.ORCID 0000-0001-9328-8514
Xue GengFirst Division, Department of Cardiology, The Second Hospital of Hebei Medical University, Heping West Road No. 215, Shijiazhuang, 050000, Hebei province, China.ORCID 0000-0001-9601-2476
Qian WangFirst Division, Department of Cardiology, The Second Hospital of Hebei Medical University, Heping West Road No. 215, Shijiazhuang, 050000, Hebei province, China.ORCID 0000-0002-7645-9518
Wei CuiFirst Division, Department of Cardiology, The Second Hospital of Hebei Medical University, Heping West Road No. 215, Shijiazhuang, 050000, Hebei province, China. cuiweihb2h@163.com.ORCID 0000-0002-2480-8667
Hebei Medical University · CNHebei General Hospital · CNBaoding People's Hospital · CNCangzhou Central Hospital · CNChengde Medical University · CNFirst Hospital of Qinhuangdao · CNFirst Hospital of Shijiazhuang · CNHandan College · CNHengshui University · CNHospital of Hebei Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew prognostic risk scores (PRSs) have been routinely used in acute decompensated heart failure (ADHF). We, therefore, externally validated three published PRSs (3A3B, AHEAD, and OPTIME-CHF) and derived a new PRS to predict the short-term prognosis in ADHF.

methodsA total of 4550 patients from the Heb-ADHF registry in China were randomly divided into the derivation and validation cohorts (3:2). Discrimination of each PRS was assessed by the area under the receiver operating characteristic curve (AUROC). Logistic regression was exploited to select the predictors and create the new PRS. The Hosmer-Lemeshow goodness-of-fit test was used to assess the calibration of the new PRS.

resultsThe AUROCs of the 3A3B, AHEAD, and OPTIME-CHF score in the derivation cohort were 0.55 (95% CI 0.53-0.57), 0.54 (95% CI 0.53-0.56), and 0.56 (95% CI 0.54-0.57), respectively. After logistic regression analysis, the new PRS computed as 1 × (diastolic blood pressure < 80 mmHg) + 2 × (lymphocyte > 1.11 × 10

conclusionsThe short-term prognostic values of 3A3B, AHEAD, and OPTIME-CHF score in ADHF patients were all poor, while the new PRS exhibited potential predictive ability. We demonstrated the QRS fraction of electrocardiogram as a novel predictor for the short-term outcomes of ADHF for the first time. Our findings might help to recognize high-risk ADHF patients.

Indexed as

Heart FailureAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsHumansNatriuretic Peptide, BrainPeptide FragmentsPrognosisRisk FactorsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsNatriuretic Peptide, BrainPeptide FragmentsAcute decompensated heart failurePrognosisRisk scoreShort-term

Identifiers

PMID35799104
PMCPMC9264535
OpenAlexW4284713779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.