Evidence map›Paper›PMID 35799081›Full record

ReviewPharmaceutical research2022

Lipocalin-Type Prostaglandin D

Md Asrarul Islam, Rhema Khairnar, Joshua Fleishman, Kamala Thompson, Sunil Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. RNAi-mediated p38δ silencing mitigates anthracycline cardiotoxicity in female mice.American journal of physiology. Heart and circulatory physiology · 2026
    Article
  4. Article
  5. Palmitate-induced downregulation of lipocalin prostaglandin DMolecular and cellular endocrinology · 2025
    Article
  6. Review
  7. Review
  8. Prostanoids in Cardiac and Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Md Asrarul IslamDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, SAH 141A, 8000 Utopia Parkway, Queens, NY, 11439, USA.
Rhema KhairnarDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, SAH 141A, 8000 Utopia Parkway, Queens, NY, 11439, USA.
Joshua FleishmanDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, SAH 141A, 8000 Utopia Parkway, Queens, NY, 11439, USA.
Kamala ThompsonDepartment of Biology, Chemistry, and Environmental Studies, Molloy College, Rockville Centre, NY, 11571, USA.
Sunil KumarDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, SAH 141A, 8000 Utopia Parkway, Queens, NY, 11439, USA. kumars2@stjohns.edu.ORCID http://orcid.org/0000-0002-5314-2673
St. John's University · USMolloy College · US

Funding

St. John's University Internal New Investigator Funding
6 · The paper itself

Abstract

Lipocalin-type prostaglandin D synthase was previously known as β-trace protein (BTP), a low-molecular-weight glycoprotein that is heavily expressed in human cerebrospinal fluid. Nevertheless, it is also seen to be expressed in numerous other tissues including the kidney, liver, lung, heart, adipose, muscle, and pancreas. Functionally, L-PGDS behaves like a lipocalin type protein where it helps in binding and transportation of small lipophilic substances, such as steroids, retinoids, and other lipophilic ligands. Enzymatically, L-PGDS functions as a prostaglandin synthase where it helps in the production of PGD

Indexed as

Liver DiseasesProstaglandin D2HumansIntramolecular OxidoreductasesLipocalinsIntramolecular OxidoreductasesLipocalinsProstaglandin D2prostaglandin R2 D-isomeraseAdipocytesInsulin ResistanceL-PGDSNon-Alcoholic Fatty Liver Disease (NAFLD)ObesitySkeletal Muscle Atrophy

Identifiers

PMID35799081
OpenAlexW4284889764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.