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Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

Baseline health-related quality of life predicts falls: a secondary analysis of a randomized controlled trial.

Jennifer C Davis, Chun Liang Hsu, Cheyenne Ghag, Samantha Y Starkey, Patrizio Jacova, Larry Dian, Naaz Parmar, Kenneth Madden, Teresa Liu-Ambrose

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00323596 completednot on this map

Action Seniors!: A 12-month Randomized Controlled Trial of a Home Based Strength and Balance Retraining Program in Reducing Falls Risk Factors

TypeobservationalSponsorUniversity of British ColumbiaRan2004 to 2008Enrolled71ConditionsFallsArmsphysical activity program of strength and balance retraining
NCT01029171 nacompletednot on this map

"Action Seniors!: A 12 Month Randomized Controlled Trial of a Home Based Strength and Balance Retraining Program in Reducing Falls.

TypeinterventionalSponsorUniversity of British ColumbiaRan2009 to 2018Enrolled344ConditionsFallsArmsHome-based balance and strength retraining exercise program., control, usual care
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prevalent falls, fall frequencies and health-related quality of life among community-dwelling older Chinese adults.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer C DavisApplied Health Economic Laboratory, Faculty of Management, University of British Columbia, 1137 Alumni Avenue, Kelowna, BC, V1V 1V7, Canada. jennifer.davis@ubc.ca.ORCID http://orcid.org/0000-0002-5274-4293
Chun Liang HsuAging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Cheyenne GhagAging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Samantha Y StarkeyAging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Patrizio JacovaAging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Larry DianFaculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Naaz ParmarDepartment of Medicine, Division of Geriatric Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Kenneth MaddenDepartment of Medicine, Division of Geriatric Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Teresa Liu-AmbroseAging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.

Funding

CIHR MOP-110954
6 · The paper itself

Abstract

purposeAmong older adults, health-related quality of life (HRQoL) and falls are associated. Generic patient-reported outcomes measures (PROMs) assess individual's HRQoL. The role for PROMs, a potential tool for predicting subsequent falls, remains under-explored. Our primary aim was to determine whether a baseline PROMs assessment of HRQoL may be a useful tool for predicting future falls.

methodsA secondary analysis of a 12-month randomized clinical trial (RCT) of a home-based exercise program among 344 adults (67% female), aged ≥ 70 years, with ≥ 1 falls in the prior year who were randomized (1:1) to either a home-based exercise program (n = 172) or usual care (n = 172). A negative binomial regression model with total falls count as the dependent variable evaluated the main effect of the independent variable-baseline HRQoL (measured by the Short-Form-6D)-controlling for total exposure time and experiment group (i.e., exercise or usual care) for the total sample. For the usual care group alone, the model controlled for total exposure time.

resultsFor the total sample, the rate of subsequent total falls was significantly predicted by baseline HRQoL (IRR = 0.044; 95% CI [0.005-0.037]; p = .004). For the usual care group, findings were confirmed with wider confidence intervals and the rate of prospective total falls was significantly predicted by baseline HRQoL (IRR = 0.025; 95% CI [0.001-0.909]; p = .044).

conclusionThese findings suggest the ShortForm-6D should be considered as part of falls prevention screening strategies within a Falls Prevention Clinic setting. Trial Registrations ClinicalTrials.gov Protocol Registration System. Identifier: NCT01029171; URL: https://clinicaltrials.gov/ct2/show/NCT01029171 . Identifier: NCT00323596; URL: https://clinicaltrials.gov/ct2/show/NCT00323596 .

Indexed as

Exercise TherapyQuality of LifeAgedExerciseFemaleHumansMaleFallsHealth-related quality of lifeOlder adultsPatient-reported outcomes measureSF-6D

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.