Evidence map›Paper›PMID 35798817›Full record

ArticleScientific reports2022

Lipid absorption and overall intestinal lymphatic transport are impaired following partial small bowel resection in mice.

Emily J Onufer, Rafael S Czepielewski, Yong-Hyun Han, Cathleen M Courtney, Stephanie Sutton, Anne Sescleifer, Gwendalyn J Randolph, Brad W Warner

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. GPR182 is a lipoprotein receptor for dietary fat absorption.The Journal of clinical investigation · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Emily J OnuferDivision of Pediatric Surgery, Department of Surgery, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Rafael S CzepielewskiDepartment of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
Yong-Hyun HanDepartment of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
Cathleen M CourtneyDivision of Pediatric Surgery, Department of Surgery, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Stephanie SuttonDivision of Pediatric Surgery, Department of Surgery, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Anne SescleiferSt. Louis University School of Medicine, St. Louis, MO, USA.
Gwendalyn J RandolphDepartment of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
Brad W WarnerDivision of Pediatric Surgery, Department of Surgery, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. brad.warner@wustl.edu.
St. Louis Children's Hospital · USWashington University in St. Louis · USKangwon National University · KRSaint Louis University · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Pediatric Gastroenterology Research Training ProgramT32DK077653 · NIDDK · WASHINGTON UNIVERSITY · PI PHILLIP I TARR · 2007 to 2026
$5.8M
Differentiation/migratory fate of monocyte-derived cellsR01AI049653 · NIAID · WASHINGTON UNIVERSITY · PI Gwendalyn J Randolph · 2000 to 2026
$4.6M
DIFFERENTIATION AND FUNCTION OF MONOCYTES AND MACROPHAGESR37AI049653 · NIAID · WASHINGTON UNIVERSITY · PI RANDOLPH, GWENDALYN J · 2016 to 2025
$4.3M
Lymphatic remodeling and transport of dietary fats in short gut syndromeR01DK119147 · NIDDK · WASHINGTON UNIVERSITY · PI Bahaa Elgendy, Ajay K. Jain · 2019 to 2026
$4.0M
Role of bile acid receptors FXR and TGR5 in preventing injury in short bowel syndromeR01DK131136 · NIDDK · SAINT LOUIS UNIVERSITY · PI JAIN, AJAY K. · 2021 to 2025
$1.9M
NCATS NIH HHS UL1 TR002345NIAID NIH HHS AI049653 20S1NIAID NIH HHS R01 AI049653NIAID NIH HHS R37 AI049653NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK052574NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK119147NIDDK NIH HHS R01 DK131136NIDDK NIH HHS T32 DK077653NIH HHS DK077653NIH HHS P30DK52574
6 · The paper itself

Abstract

Short bowel syndrome (SBS) is associated with diminished levels of serum fats caused by unknown mechanisms. We have shown that mesenteric lymphatics remodel to a more primitive state one week after small bowel resection (SBR); therefore, this study focuses on the effect of chronic lymphatic remodeling and magnitude of resection on intestinal lipid uptake and transport. C57BL6 and Prox1 creER-Rosa26

Indexed as

Intestinal DiseasesLymphatic VesselsShort Bowel SyndromeAnimalsIntestinal AbsorptionIntestinesLipidsMiceMice, Inbred C57BLLipids

Identifiers

PMID35798817
PMCPMC9262882
OpenAlexW4284675150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.