ArticleScientific reports2022
Longitudinal changes in auditory and reward systems following receptive music-based intervention in older adults.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Music-based interventions for chronic pain management.The Cochrane database of systematic reviews · 2026Pooled it
- Effectiveness of music therapy for children with autism spectrum disorder: meta-analysis and potential biological mechanisms.Frontiers in psychiatry · 2025Pooled it
- Topical Cellular/Tissue and Molecular Aspects Regarding Nonpharmacological Interventions in Alzheimer's Disease-A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Music Therapy for Reduction of Anhedonia: Protocol for a Sequential Mixed Methods Pre-Post Pilot Study.JMIR research protocols · 2026Article
- Musical Training Amplifies Food Cue-Related Interference in Working Memory.Behavioral sciences (Basel, Switzerland) · 2026Article
- Musicality is Preserved in Neurodegeneration.The Yale journal of biology and medicine · 2026Review
- Potential Effects of Music on Non-Motor Symptoms in Parkinson's Disease: Translating Mechanisms to Therapy.Neurology international · 2026Review
- Music activities that most elicit interest and pleasure among older people with mild-to-moderate dementia: a qualitative multiple-case study in Italy.Frontiers in aging neuroscience · 2026Article
- Functional Connectivity of Auditory, Motor, and Reward Networks at Rest and During Music Listening.Brain sciences · 2025Article
- Mapping the brain networks underlying creativity enhancement via aesthetic experience.European journal of medical research · 2025Review
- Neuroimaging and neuroelectrophysiological features of music's effects on anhedonia in major depressive disorder: A minireview.World journal of psychiatry · 2025Review
- Dance-like state detection, curiosity, and decentering: A pilot study on artful movement and mindfulness.Journal of Alzheimer's disease : JAD · 2025Article
- Improving executive functioning and reducing the risk of Alzheimer's disease with music therapy: A narrative review of potential neural mechanisms.Journal of Alzheimer's disease : JAD · 2025Review
- Music-Evoked Nostalgia Activates Default Mode and Reward Networks Across the Lifespan.Human brain mapping · 2025Article
- Diary Analysis of an RCT: Natural Language Analyses of Gamma-Music-Based Intervention.Music and medicine · 2025Article
- Music-induced cognitive change and whole-brain network flexibility: a pilot study.Frontiers in neuroscience · 2025Article
- Music reward sensitivity is associated with greater information transfer capacity within dorsal and motor white matter networks in musicians.Brain structure & function · 2024Article
- Transforming text to music using artificial intelligence improves the frontal lobe function of normal older adults.Brain and behavior · 2024Article
- Network connectivity differences in music listening among older adults following a music-based intervention.bioRxiv : the preprint server for biology · 2024Article
- Revisiting the musical reminiscence bump: insights from neurocognitive and social brain development in adolescence.Frontiers in psychology · 2024Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Listening to pleasurable music is known to engage the brain's reward system. This has motivated many cognitive-behavioral interventions for healthy aging, but little is known about the effects of music-based intervention (MBI) on activity and connectivity of the brain's auditory and reward systems. Here we show preliminary evidence that brain network connectivity can change after receptive MBI in cognitively unimpaired older adults. Using a combination of whole-brain regression, seed-based connectivity analysis, and representational similarity analysis (RSA), we examined fMRI responses during music listening in older adults before and after an 8-week personalized MBI. Participants rated self-selected and researcher-selected musical excerpts on liking and familiarity. Parametric effects of liking, familiarity, and selection showed simultaneous activation in auditory, reward, and default mode network (DMN) areas. Functional connectivity within and between auditory and reward networks was modulated by participant liking and familiarity ratings. RSA showed significant representations of selection and novelty at both time-points, and an increase in striatal representation of musical stimuli following intervention. An exploratory seed-based connectivity analysis comparing pre- and post-intervention showed significant increase in functional connectivity between auditory regions and medial prefrontal cortex (mPFC). Taken together, results show how regular music listening can provide an auditory channel towards the mPFC, thus offering a potential neural mechanism for MBI supporting healthy aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.