GuidelineGut2022
British Society of Gastroenterology guidelines on the management of functional dyspepsia.
Guideline in Gut, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 4 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- Physical-based therapy for the treatment of functional dyspepsia: a systematic review.Clinical journal of gastroenterology · 2026Pooled it
- Second Asian Consensus Report on Functional Dyspepsia (2025): Updated Recommendations.Journal of gastroenterology and hepatology · 2026Pooled it
- Efficacy and safety of Xiangsha liujunzi decoction for functional dyspepsia: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- Efficacy of acupuncture for anxiety and depression in functional dyspepsia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Evaluation of safety and efficacy of the combination of mebeverine and sulpiride in treatment of patients with functional gastrointestinal disorders: A prospective cohort.The Journal of international medical research · 2026Trial
- Functional dyspepsia and risk of Barrett's esophagus and dysplasia: A propensity-matched multicenter retrospective cohort study.World journal of methodology · 2026Article
- The Role of Diet in Functional Dyspepsia.Nutrients · 2026Review
- Simotang oral liquid alleviates functional dyspepsia-related motility dysfunction through CaJournal of food and drug analysis · 2026Article
- Age threshold and symptoms are useful for scheduling upper endoscopy in clinical practice.Internal and emergency medicine · 2026Article
- Medication-safety burden of omeprazole in psychiatric inpatients: A retrospective cross-sectional study.The Journal of international medical research · 2026Article
- Physical Activity as a Therapeutic Strategy for Functional Dyspepsia.Journal of neurogastroenterology and motility · 2026Article
- Expert Clinical Consensus on Body Surface Gastric Mapping Phenotypes for Gastroduodenal Disorders: 'Auckland Classification' v1.0.Neurogastroenterology and motility · 2026Article
- Functional Reconstruction of the Gut Microecosystem in Gastrointestinal Motility Disorders: Roles of Probiotics, Prebiotics, Synbiotics and Postbiotics.Probiotics and antimicrobial proteins · 2026Review
- Dyspepsia Care as a Missed Gateway to Gastric Cancer Prevention in High-Risk U.S. Populations.Journal of immigrant and minority health · 2026Article
- Gastric cancer secondary prevention in dyspeptic patients.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- Rome V Pediatric Upper Gastrointestinal Disorders of Gut-Brain Interaction.Gastroenterology · 2026Review
- Review
- Development and validation of a novel blood-based biomarker for gastric cancer triage in chronic dyspepsia.NPJ digital medicine · 2026Article
- Article
- Diagnosis of Functional Dyspepsia and Novel Gastrointestinal Functional Assessments.Digestion · 2026Review
24 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
13 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional dyspepsia (FD) is a common disorder of gut-brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline for the management of dyspepsia was published in 1996. In the interim, substantial advances have been made in understanding the complex pathophysiology of FD, and there has been a considerable amount of new evidence published concerning its diagnosis and classification, with the advent of the Rome IV criteria, and management. The primary aim of this guideline, commissioned by the BSG, is to review and summarise the current evidence to inform and guide clinical practice, by providing a practical framework for evidence-based diagnosis and treatment of patients. The approach to investigating the patient presenting with dyspepsia is discussed, and efficacy of drugs in FD summarised based on evidence derived from a comprehensive search of the medical literature, which was used to inform an update of a series of pairwise and network meta-analyses. Specific recommendations have been made according to the Grading of Recommendations Assessment, Development and Evaluation system. These provide both the strength of the recommendations and the overall quality of evidence. Finally, in this guideline, we consider novel treatments that are in development, as well as highlighting areas of unmet need and priorities for future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.