Evidence map›Paper›PMID 35798369›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2022

Shen Cheng, Darcy R Flora, Allan E Rettie, Richard C Brundage, Timothy S Tracy

Open access · bronzeAbstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Recombinant Technologies Facilitate Drug Metabolism, Pharmacokinetics, and General Biomedical Research.Drug metabolism and disposition: the biological fate of chemicals · 2023
    Review
  6. Article
  7. Drug metabolism and disposition: the biological fate of chemicals · 2022
    Article
  8. Drug-Drug-Gene Interactions in Cardiovascular Medicine.Pharmacogenomics and personalized medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shen ChengMetrum Research Group, United States.ORCID 0000-0002-7493-4784
Darcy R FloraPresent Affiliation: GRYT Health Inc., United States.
Allan E RettieDept. of Medicinal Chemistry, University of Washington, United States.
Richard C BrundageExperimental and Clinical Pharmacology, University of Minnesota, United States brund001@umn.edu.ORCID 0000-0003-4465-5036
Timothy S TracyTracy Consultants, United States.
University of Minnesota · US

Funding

TOXIC DRUG INTERACTIONS WITH VALPROIC ACIDP01GM032165 · NIGMS · UNIVERSITY OF WASHINGTON · PI RETTIE, ALLAN EDWARD · 1985 to 2012
$18.3M
Pharmacogenetics and Drug InteractionsR01GM069753 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BRUNDAGE, RICHARD C · 2004 to 2012
$2.5M
NIGMS NIH HHS P01 GM032165NIGMS NIH HHS R01 GM069753
6 · The paper itself

Abstract

The objective of this study is to characterize the impact of

Indexed as

drug-drug interactionsgenetic polymorphismpharmacokinetic modeling

Identifiers

PMID35798369
PMCPMC9488981
OpenAlexW4284711870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.