ArticleEnvironmental research2022
Impacts of long-term ambient particulate matter and gaseous pollutants on circulating biomarkers of inflammation in male and female health professionals.
Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Prenatal and postnatal household air pollution and longitudinal growth trajectories: results from long-term follow up of the GRAPHS cohort.Environment international · 2026Article
- Associations of fine particulate matter pollution components with overall, prostate cancer, and cardiovascular disease mortality in men with prostate cancer: A cohort study.Environmental research · 2026Article
- Air Pollution and Parkinson's Disease Pathology: Clinical Evidence and the Molecular Mechanisms Linking Airborne Toxicants to Neuroinflammation and Neurodegeneration.Parkinson's disease · 2026Review
- Effect of ambient particulate matter pollution on disease burden globally: a systematic analysis of the global burden of disease study 2021.BMC public health · 2025Article
- Ambient air pollution and survival among Black women with epithelial ovarian cancer across diverse geographical regions of the United States.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Article
- Residential greenness and diabetes incidence in two prospective cohorts of US women.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Cross-sectional Associations of Neighborhood Social and Environmental Contextual Factors with Telomere Length in Male and Female Health Professionals.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Long-Term Exposure to Air Pollution and Incidence of Type 2 Diabetes in the Nurses' Health Study and Nurses' Health Study II.Environmental health perspectives · 2025Article
- The Association between Multiple Environmental Exposures and Symptoms of Generalized Anxiety Disorder in a Prospective, US-Based Cohort Study.Environmental health perspectives · 2025Article
- Article
- Neighborhood greenness and long-term physical and psychosocial quality of life among prostate cancer survivors in the Health Professionals Follow-up Study.Environmental research · 2024Article
- Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions.Circulation research · 2024Review
- Coarse Particulate Matter and Markers of Inflammation and Coagulation in the Multi-Ethnic Study of Atherosclerosis (MESA) Population: A Repeat Measures Analysis.Environmental health perspectives · 2024Article
- Associations between air pollution, residential greenness, and glycated hemoglobin (HbA1c) in three prospective cohorts of U.S. adults.Environmental research · 2023Article
- Review
- Particulate matter, traffic-related air pollutants, and circulating C-reactive protein levels: The Multiethnic Cohort Study.Environmental pollution (Barking, Essex : 1987) · 2023Article
- Assessing the timing and the duration of exposure to air pollution on cardiometabolic biomarkers in patients suspected of coronary artery disease.Environmental research · 2023Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundSystemic inflammation may serve as a biological mechanism linking air pollution to poor health but supporting evidence from studies of long-term pollutant exposure and inflammatory cytokines is inconsistent.
objectiveWe studied associations between multiple particulate matter (PM) and gaseous air pollutants and pro- and anti-inflammatory cytokines within two nationwide cohorts of men and women.
methodsData were obtained from 16,151 women in the Nurses' Health Study and 7,930 men in the Health Professionals' Follow-up Study with at least one measure of circulating adiponectin, C-Reactive Protein (CRP), Interleukin-6 (IL-6) or soluble tumor necrosis-factor receptor-2 (sTNFR-2). Exposure to PM with aerodynamic diameter ≤2.5, 2.5-10, and ≤10 μm (PM
resultsIn adjusted models, we observed a 2.72% (95% CI: 0.43%, 5.95%), 3.11% (-0.12%, 6.45%), and 3.67% (0.19%, 7.26%) increase in CRP associated with a 10 μg/m
conclusionsAcross multiple long-term pollutant exposures and inflammatory markers, associations were generally weak. Focusing on specific pollutant-inflammatory mechanisms may clarify pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.