Evidence map›Paper›PMID 35796988›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

In Vitro Selection of Deoxyribozymes for the Detection of RNA Modifications.

Anam Liaqat, Maksim V Sednev, Claudia Höbartner

Open access · hybridAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anam LiaqatInstitute of Organic Chemistry, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Maksim V SednevInstitute of Organic Chemistry, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Claudia HöbartnerInstitute of Organic Chemistry, Julius-Maximilians-University Würzburg, Würzburg, Germany. claudia.hoebartner@uni-wuerzburg.de.
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deoxyribozymes are artificially evolved DNA molecules with catalytic abilities. RNA-cleaving deoxyribozymes have been recognized as an efficient tool for detection of modifications in target RNAs and provide an alternative to traditional and modern methods for detection of ribose or nucleobase methylation. However, there are only few examples of DNA enzymes that specifically reveal the presence of a certain type of modification, including N

Indexed as

DNA, CatalyticDNAGene LibraryMethylationRNADNADNA, CatalyticRNACatalytic DNADeoxyribozymesEpitranscriptomicsIn vitro selectionModified RNA nucleotidesRNARNA cleavage

Identifiers

PMID35796988
PMCPMC9761555
OpenAlexW4285048723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.