Evidence map›Paper›PMID 35796875›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2022

Phototoxicity of BODIPY in long-term imaging can be reduced by intramolecular motion.

Iida Kähärä, Nikita Durandin, Polina Ilina, Alexander Efimov, Timo Laaksonen, Elina Vuorimaa-Laukkanen, Ekaterina Lisitsyna

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Iida KähäräChemistry and Advanced Materials, Unit of Materials Science and Environmental Engineering, Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, 33014, Tampere, Finland. iida.kahara@tuni.fi.ORCID http://orcid.org/0000-0002-3000-3208
Nikita DurandinChemistry and Advanced Materials, Unit of Materials Science and Environmental Engineering, Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, 33014, Tampere, Finland.
Polina IlinaDivision of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, 00014, Helsinki, Finland.
Alexander EfimovChemistry and Advanced Materials, Unit of Materials Science and Environmental Engineering, Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, 33014, Tampere, Finland.
Timo LaaksonenChemistry and Advanced Materials, Unit of Materials Science and Environmental Engineering, Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, 33014, Tampere, Finland.
Elina Vuorimaa-LaukkanenChemistry and Advanced Materials, Unit of Materials Science and Environmental Engineering, Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, 33014, Tampere, Finland.
Ekaterina LisitsynaChemistry and Advanced Materials, Unit of Materials Science and Environmental Engineering, Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, 33014, Tampere, Finland. ekaterina.lisitsyna@tuni.fi.
Tampere University · FIUniversity of Helsinki · FI

Funding

Academy of Finland 311362Academy of Finland 316893Academy of Finland 323669
6 · The paper itself

Abstract

For long-term live-cell fluorescence imaging and biosensing, it is crucial to work with a dye that has high fluorescence quantum yield and photostability without being detrimental to the cells. In this paper, we demonstrate that neutral boron-dipyrromethene (BODIPY)-based molecular rotors have great properties for high-light-dosage demanding live-cell fluorescence imaging applications that require repetitive illuminations. In molecular rotors, an intramolecular rotation (IMR) allows an alternative route for the decay of the singlet excited state (S

Indexed as

BoronBoron CompoundsMolecular ProbesOxygenPorphobilinogen4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoronBoron CompoundsdipyrrometheneMolecular ProbesOxygenPorphobilinogenBoron-dipyrromethene (BODIPY)Intramolecular rotation (IMR)PhototoxicitySinglet oxygenViability assay

Identifiers

PMID35796875
OpenAlexW4284687001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.