Evidence map›Paper›PMID 35796611›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

Oxidative stress contributes to reductions in microvascular endothelial- and nitric oxide-dependent dilation in women with a history of gestational diabetes.

Anna E Stanhewicz, Rowan L Schlarmann, Kaila M Brustkern, Diana I Jalal

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparing cutaneous NO-dependent vasodilation between young males and females.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Impaired microvascular insulin-dependent dilation in women with a history of gestational diabetes.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna E StanhewiczDepartment of Health and Human Physiology, The University of Iowa, Iowa City, Iowa.ORCID 0000-0002-3941-3879
Rowan L SchlarmannDepartment of Health and Human Physiology, The University of Iowa, Iowa City, Iowa.
Kaila M BrustkernDepartment of Health and Human Physiology, The University of Iowa, Iowa City, Iowa.
Diana I JalalIowa City Veterans Affairs Health Care System, Iowa City, Iowa.
University of Iowa · US

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR002537NCATS NIH HHS UL1 TR002537UI Fraternal Order of Eagles Diabetes Research Center
6 · The paper itself

Abstract

Women with a history of gestational diabetes mellitus (GDM) are twice as likely to develop cardiovascular disease (CVD) and ∼7 times as likely to develop type 2 diabetes as their age-matched counterparts. However, the mechanism(s) mediating these associations remain unclear. We hypothesized that endothelium- and (nitric oxide) NO-dependent dilation would be attenuated through oxidant stress mechanisms in the microvasculature of women with a history of GDM compared with control women with a history of uncomplicated pregnancy (HC). Ten HC (35 ± 4 yr) and 10 GDM (34 ± 4 yr) underwent a standard local heating protocol (42°C; 0.1°C·s

Indexed as

Cardiovascular DiseasesDiabetes, GestationalDiabetes Mellitus, Type 2Ascorbic AcidDilatationEndotheliumFemaleHumansNitric OxideOxidative StressPregnancyRegional Blood FlowSkinVasodilationAscorbic AcidNitric Oxideendothelial dysfunctiongestational diabetesmicrovasculaturenitric oxide

Identifiers

PMID35796611
PMCPMC9359638
OpenAlexW4284880268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.