Evidence map›Paper›PMID 35796436›Full record

ArticleeLife2022

Morphogenetic forces planar polarize LGN/Pins in the embryonic head during

Jaclyn Camuglia, Soline Chanet, Adam C Martin

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jaclyn CamugliaBiology Department, Massachusetts Institute of Technology, Cambridge, MA, United States.ORCID 0000-0001-9268-9471
Soline ChanetCenter for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Université PSL, Paris, France.ORCID 0000-0002-4065-9411
Adam C MartinBiology Department, Massachusetts Institute of Technology, Cambridge, MA, United States.ORCID 0000-0001-8060-2607
Massachusetts Institute of Technology · USCentre National de la Recherche Scientifique · FR

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Tissue morphogenesis: From signals to forcesR35GM144115 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Adam Christopher Martin · 2022 to 2026
$3.0M
Investigating the generation of mechanical forces during tissue invaginationR01GM105984 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MARTIN, ADAM CHRISTOPHER · 2013 to 2021
$2.4M
NIGMS NIH HHS R01 GM105984NIGMS NIH HHS R35 GM144115NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle. Cortical Pins/LGN recruitment serves as a critical step in this process. Here, we identify Pins-mediated planar cell polarized divisions in several of the mitotic domains of the early

Indexed as

DrosophilaDrosophila ProteinsAnimalsCell Cycle ProteinsCell PolarityGastrulationProtein BindingSpindle ApparatusCell Cycle ProteinsDrosophila Proteinsadherens junctionscell biologydevelopmental biologyD. melanogasterDrosophilamechanicsmorphogenesisPins/LGNspindle orientation

Identifiers

PMID35796436
PMCPMC9262390
OpenAlexW4284695133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.