Evidence map›Paper›PMID 35796425›Full record

ArticleeLife2022

Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator.

Ryan S Phillips, Hidehiko Koizumi, Yaroslav I Molkov, Jonathan E Rubin, Jeffrey C Smith

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Review
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  8. Interdependence of cellular and network properties in respiratory rhythm generation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Role of NaCell reports · 2023
    Article
  12. Microcircuit Synchronization and Heavy-Tailed Synaptic Weight Distribution Augment preBötzinger Complex Bursting Dynamics.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ryan S Phillips *Department of Mathematics, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0002-8570-2348
Hidehiko Koizumi *Cellular and Systems Neurobiology Section, NINDS, NIH, Bethesda, United States.ORCID 0000-0002-7747-3434
Yaroslav I MolkovDepartment of Mathematics and Statistics, Georgia State University, Atlanta, United States.ORCID 0000-0002-0862-1974
Jonathan E RubinDepartment of Mathematics, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0002-1513-1551
Jeffrey C SmithCellular and Systems Neurobiology Section, NINDS, NIH, Bethesda, United States.ORCID 0000-0002-7676-4643
University of Pittsburgh · USGeorgia State University · US

Funding

Neural Mechanisms Controlling Breathing In MammalsZIANS002899 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SMITH, JEFFREY C · 2009 to 2023
$21.1M
Multi-Scale Models of Neural Mechanisms Controlling Breathing in MammalsZIANS003108 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SMITH, JEFFREY C · 2009 to 2023
$7.5M
Modeling Brainstem Inflammation's Role in Systemic Dysfunction during SepsisU01EB021960 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DICK, THOMAS E · 2017 to 2020
$2.6M
CRCNS: Modeling the respiratory-sympathetic coupling in neurogenic hypertensionR01AT008632 · NCCIH · INDIANA UNIVERSITY INDIANAPOLIS · PI MOLKOV, YAROSLAV · 2015 to 2019
$1.4M
NCCIH NIH HHS R01 AT008632NIBIB NIH HHS U01 EB021960
6 · The paper itself

Abstract

Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (I

Indexed as

Biological ClocksMedulla OblongataAnimalsMammalsMiceNeuronsRespiratory RateRespiratory Systemcomputational modelingmouseneurosciencepattern generationpreBӧtzinger complexrespiratory rhythm generation

Identifiers

PMID35796425
PMCPMC9262387
OpenAlexW4283818029

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.