Evidence map›Paper›PMID 35796019›Full record

Trial reportThe Journal of asthma : official journal of the Association for the Care of Asthma2023

Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial.

Janneane F Gent, Theodore R Holford, Michael B Bracken, Julie M Plano, Lisa A McKay, Keli M Sorrentino, Petros Koutrakis, Brian P Leaderer

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of asthma : official journal of the Association for the Care of Asthma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02258893 (Indoor Nitrogen Dioxide Exposure and Children With Asthma), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02258893 nacompletednot on this map

Indoor Nitrogen Dioxide Exposure and Children With Asthma: An Intervention Trial

TypeinterventionalSponsorYale UniversityRan2016 to 2019Enrolled116ConditionsAsthmaArmsNO2 Scrubber, HEPA filter, Control
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Janneane F GentThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Theodore R HolfordThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Michael B BrackenThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Julie M PlanoThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Lisa A McKayThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Keli M SorrentinoThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0003-4118-6473
Brian P LeadererThe Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Providence Center · USHarvard University · US

Funding

Indoor Nitrogen Dioxide Exposure and Children with Asthma: An Intervention TrialR01ES023505 · NIEHS · YALE UNIVERSITY · PI BRACKEN, MICHAEL B, GENT, JANNEANE FERGUSON · 2014 to 2018
$4.6M
NIEHS NIH HHS R01 ES023505
6 · The paper itself

Abstract

objectiveTriple-crossover randomized controlled intervention trial to test whether reduced exposure to household NO

methodsChildren (

resultsMeasured NO

conclusionsIt remains unknown if using an air cleaner alone can achieve levels of NO REGISTRATION NUMBER: NCT02258893.

Indexed as

Air PollutantsAir Pollution, IndoorAsthmaChildHousehold ProductsHumansMassachusettsNitrogen DioxideParticulate MatterAir PollutantsNitrogen DioxideParticulate Matterair cleanerasthma symptomsChildrengas stoveshousehold NO2persistent asthmaRCT

Identifiers

PMID35796019
PMCPMC10162040
OpenAlexW4284666232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.